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Name: Celine Pinheiro

Office: I1.17

School Phone: +351 253 604 872

Email: cpinheiro@med.uminho.pt

 

 

 

Keywords: Cancer metabolism Monocarboxylate transporters Hipoxia

About

Research interests:
Oncobiology; Cancer metabolism; Exploitation of MCTs (monocarboxylate transporters) as new targets for cancer therapy.

Selected Publications

Pinheiro C, Longatto-Filho A, Nogueira R, Schmitt F, Baltazar F. Lactate-induced IL-8 pathway in endothelial cells--letter. Cancer Res. 2012 Apr 1;72(7):1901-2; author reply 1903-4. doi: 10.1158/0008-5472.CAN-11-1540.

Miranda-Gonçalves V, Granja S, Martinho O, Honavar M, Pojo M, Costa BM, Pires MM, Pinheiro C, Cordeiro M, Bebiano G, Costa P, Reis RM, Baltazar F. Hypoxia-mediated upregulation of MCT1 expression supports the glycolytic phenotype of glioblastomas. Oncotarget, 2016; 7(29):46335-46353

Miranda-Gonçalves V, Honavar M, Pinheiro C, Martinho O, Cordeiro M, Bebiano G, Costa P, Reis RM, Baltazar F. Monocarboxylate transporters (MCTs) in gliomas: Expression and exploitation as therapeutic target. Neuro-Oncology, 2013;15(2):172-88.

Morais-Santos F, Miranda-Gonçalves V, Pinheiro S, Vieira AF, Paredes J, Schmitt F, Baltazar F*, Pinheiro C*. Differential sensitivities to lactate transport inhibitors of breast cancer cell lines. Endocr Relat Cancer, 2014; 21(1): 27-38.

Sousa S, Granja S, Pinheiro C, Fernandes D, Longatto-Filho A, Laus AC, Alves CDC, Suárez-Peñaranda JM, Pérez-Sayáns M, Carvalho AL, Schmitt FC, García-García A, Baltazar F. Prognostic significance of monocarboxylate transporter expression in oral cavity tumors. Cell cycle, 2016; 15(14):1865-73

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