Mónica Morais is graduated in Genetic and Biotechnology by the University of Trás-os-Montes e Alto Douro. Subsequently, she developed her master thesis in the Faculty of Medicine, University of Porto in the area of CFTR mutations in infertility patients under the supervision of Professor Mário Sousa (ICBAS/FMUP).
Mónica started her research work in the Neurocience Domain of ICVS in February 2010. During this time she has been involved in different projects addressing distinct aspects of the Neurobiology of Depression.
She is currently a PhD student in ICVS (under the supervision of João Bessa, MD PhD and Nuno Sousa, MD PhD) and the main focus of her research is study the impactof antipsychotic drugs in neuroplasticity.
Cumulative stress: the link between depression and dementia
Lopes S, Teplytska L, Vaz-Silva J, Dioli C, Trindade R, Morais M, Webhofer C, Almeida OFX, Turck C, Sousa N, Sotiropoulos I, Filiou MD. Tau deletion prevents stress-induced dendritic atrophy in prefrontal cortex: role of synaptic mitochondria. Cereb Cortex, in press
Patrício P, Mateus-Pinheiro A, Irmler M, Alves ND, Machado-Santos AR, Morais M, Correia JS, Korostynski M, Piechota M, Stoffel R, Beckers J, Bessa JM, Almeida OF, Sousa N, Pinto L. Differential and converging molecular mechanisms of antidepressants action in the hippocampal dentate gyrus. Neuropsychopharmacology. 2015 Jan;40(2):338-49. doi: 10.1038/npp.2014.176. Epub 2014 Jul 18.
Mateus-Pinheiro A, Patrício P, Alves ND, Machado-Santos AR, Morais M, Bessa JM, Sousa N. Pinto L. The Sweet Drive Test: Refining phenotypic characterization of anhedonic behavior in rodents. Front Behav Neurosc, 8:74 (2014).
Monteiro S, Ferreira F, Pinto V, Roque S, Morais M, Sá-Calçada D, Mota C, Correia-Neves M, Cerqueira JJ. Absence of IFN? promotes hippocampal plasticity and enhances cognitive performance. Transl Psychiat, 6:e707 (2016).
Pinto L, Mateus-Pinheiro A, Morais M, Bessa JM, Sousa N. Immuno-Golgi as a tool for analyzing neuronal 3D-dendritic structure in phenotypically characterized neurons. PLoS One. 2012;7(3):e33114. doi: 10.1371/journal.pone.0033114. Epub 2012 Mar 12.