Research & Scientists | Microbiology & Infection | People | ID6189


Name: Joana Gaifem

Office: I3.02

School Phone: +351 253 604 834

Email: id6189@alunos.uminho.pt




Keywords: Mucosal immunology Microbiome Inflammation Metabolism


Joana Gaifem holds a degree in Biology (2009, Faculty of Sciences, University of Porto) and a Master in Environmental Contamination and Toxicology (2011, ICBAS, University of Porto). In 2012, she was a research fellow at the Bioengineering and Synthetic Microbiology Group at IBMC (Porto) in a project focused in the secondary metabolism of cyanobacteria. Between April 2013 and December 2014 she worked at the ICVS as a research fellow in a FCT/Harvard Medical School funded project to study the evasion mechanisms of host immune response by Mycobacterium tuberculosis. Currently Joana is developing her PhD project (PhDOC Program) and she is focused in deciphering the microbiome and metabolic factors that contribute to protection or susceptibility in Inflammatory Bowel Disease (IBD).

Selected Publications

Cruz A, Ludovico P, Torrado E, Gama JB, Sousa J, Gaifem J, Appelberg R, Rodrigues F, Cooper AM, Pedrosa J, Saraiva M, Castro AG. "IL-17A promotes intracellular growth of Mycobacterium by inhibiting apoptosis of infected macrophages". Front. Immunol. 6:498.

Correia CR, Gaifem J, Oliveira MB, Silvestre R, Mano JF. "The influence of surface modified poly(l-lactic acid) films on the differentiation of human monocytes into macrophages". Biomater Sci. 2017 Feb 28;5(3):551-560.

Cunha C, Gonçalves SM, Duarte-Oliveira C, Leite L, Lagrou K, Marques A, Lupiañez CB, Mesquita I, Gaifem J, Barbosa AM, Vaz CP, Branca R, Campilho F, Freitas F, Ligeiro D, Lass-Flörl C, Löffler J, Jurado M, Saraiva M, Kurzai O, Rodrigues F, Castro AG, Silvestre R, Sainz J, Maertens JA, Torrado E, Jacobsen ID, Lacerda JF, Campos A Jr., Carvalho A. “IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity”. J Allergy Clin Immunol. 2017 Sep;140(3):867-870.e9

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