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Research & Scientists | Neurosciences | People | FABIOTEIXEIRA

 

Name: Fábio Teixeira

Office: G2.25

School Phone: +351 253 604 929

Email: fabioteixeira@med.uminho.pt

 

 

 

Keywords: Regenerative Medicine - Mesenchymal Stem Cells - Stem Cells Secretome - Bioreactor Cell Culture - Stem Cells Isolation - Neurospheres Cell Culture - Animal Experimentation

About

Fábio Teixeira PhD, is a biologist that performed his PhD in Health Sciences at the Life and Health Sciences Research Institute (ICVS), ICVS/3B’s PT Government Associate Laboratory Braga/Guimarães, University of Minho. His PhD project consisted in the development of new strategies through the use of Mesenchymal Stem Cells (MSCs) and their Secretome as a new possible therapeutic strategy for the regeneration of central nervous system (CNS), in collaboration with the Pharmaceutical Production Research Facility (PPRF), University of Calgary, Canada. During his work, he held the protocol of introduction to the use of Animal House Facilities, where he acquired all the guidelines in the manipulation of the animals (i.e. handling, animal behaviour and surgical processes).In addition, he also has acquired expertise in the following techniques:cell culture, proteomic analysis, stereotaxic surgery, immunocytochemistry/immunohistochemistry, fluorescence and confocal microscopy, molecular analysis (Western blot and qRT-PCR) and animal behavioral analysis. At PPRF, he has also acquired expertise in biotechnological cell culture procedures through the use of bioreactors.Was also a team member of the project “Identification of key neuroregulatory molecules expressed by Human umbilical cord stem cells”, funded by Calouste Gulbenkian Foundation. Currently, he is in his second year as a Post-Doctoral researcher, in which his project consists in the exploration of combinatorial approaches using MSCs secretome and pharmacological strategies for Parkinson’s Disease.

As a result of his research work, he is currently an author of 14 scientific papers (h-index of 5), 2 book chapters and 21 communications in national and international conferences (oral/poster presentations).

Projects

Exploring the Therapeutic Potential of the Secretome of Mesenchymal Stem Cells in CNS Regenerative Medicine  

Selected Publications

Teixeira FG, Carvalho MM, Sousa N, Salgado AJ. Mesenchymal Stem Cells Secretome: a new paradigm for Central Nervous System Regeneration? Cell Mol Life Sci. 2013 Oct;70(20):3871-82. doi: 10.1007/s00018-013-1290-8. Epub 2013 Mar 1.

Salgado AJ, Sousa JC, Costa BM, Pires AO, Mateus Pinheiro A, Teixeira FG, Pinto L, Sousa N. Mesenchymal Stem Cells Secretome as a Modulator of the Neurogenic Niche: Basic Insights and Therapeutic Opportunities. Front Cell Neurosci, 9:249 (2015).

Salgado AJ, Sousa JC, Costa BM, Pires AO, Mateus Pinheiro A, Teixeira FG, Pinto L, Sousa N. Mesenchymal Stem Cells Secretome as a Modulator of the Neurogenic Niche: Basic Insights and Therapeutic Opportunities. Front Cell Neurosci, 9:249 (2015).

Teixeira FG*, Panchalingam KM*, Anjo Si, Manadas B, Pereira R, Sousa N, Salgado AJ**, Behie LA**. Do Hypoxia/Normoxia Culturing Conditions Change the Neuroregulatory Profile of Wharton Jelly Mesenchymal Stem Cells Secretome?. Stem Cell Res Ther, 6(1):133 (2015).

Carvalho MM, Teixeira FG, Reis RL, Sousa N, Salgado AJ. Mesenchymal stem cells in the umbilical cord: phenotypic characterization, secretome and applications in central nervous system regenerative medicine. Curr Stem Cell Res Ther. 2011 Sep;6(3):221-8.

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