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Research & Scientists | Neurosciences | People | JOANAMSILVA

 

Name: Joana Silva

Office: I2.03

School Phone: +351 253 604 835

Email: ID4535@alunos.uminho.pt

 

 

 

Keywords: Neurodegneration Proteostasis Tau Alzheimer Stress Behavior Cognition

About

Joana Silva is a PhD student at ICVS/3B’s PT-Government Associate Laboratory, atthe School of Health Science, University of Minho. Her main line of research is related with the mechanisms involved in the development of neurodegenerative disorders, mainly directed to the role of Tau protein in the development of this disorders. Her Master studies have been focused on the role of Tau protein in the progression and development of neurodegeneration, through the mechanisms involved in regulation of protein degradation and aggregation and their involvement in cell death processes like apoptosis and autophagy. Joana is currently enrolled in a project focused onthe role of Tau in the brain development and brain aging as well as initiation of neurodegeneration using novel transgenic mice models. 

Projects

Environmental stress and Alzheimer´s disease pathologies  

Sensomotor mechanisms and Alzheimer´s disease pathology  

Selected Publications

Moreira PS, Sotiropoulos I, Silva J, Takashima A, Sousa N, Leite-Almeida H, Costa PS. The advantages of Structural Equation Modelling to address the complexity of spatial reference learning. Front Behav Neurosci, 10:18 (2016).

Pinheiro S, Silva J, Mota C, Vaz-Silva J, Veloso A, Pinto V, Sousa N, Cerqueira J, Sotiropoulos I. Tau mislocation in glucocorticoid-triggered hippocampal pathology. Mol Neurobiol, 53(7):4745-4753 (2016)

Vyas S, Rodrigues AJ, Silva JM, Tronche F, Almeida OFX, Sousa N, Sotiropoulos I. Chronic Stress and Glucocorticoids: from neuronal plasticity to neurodegeneration. Neural Plasticity, 2016:6391686 (2016).

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