Neide Vieira is a Postdoctoral Fellow working at the Life and Health Sciences Research Institute (ICVS), University of Minho, Portugal.
She graduated in Applied Biology in 2005 with the highest mark (2002—2005) and completed her European PhD degree in Health Sciences in April 2010, by the University of Minho (Portugal), and the University of Aberdeen (UK). During her PhD studies, Neide Vieira focused on studying the function, physiology, and regulation of carboxylic acids transporters in pathogenic and non-pathogenic yeasts. During her PhD thesis Neide Vieira worked in the University of Minho, in the Institute of Medical Sciences in Aberdeen, Aberdeen, UK, in the Institute Jacques Monod in Paris, France and in the École Normale Supérieure in Paris, France. In 2010 Neide Vieira moved to NYC as a Postdoctoral Fellow under the supervision of Professor Tung-Tien, Sun (funded by NIH, USA) in the NYU Langone Medical Center, (USA). Neide Vieira worked on a multidisciplinary team consisting of a total of five principal investigators with diverse backgrounds, studying the trafficking, assembly, structure, function and disease implications of uroplakins. Uroplakins constitute a group of integral membrane proteins that are made as major differentiation products of bladder epithelium and are implicated on human diseases including urinary tract infections and bladder cancer. In 2012 Neide Vieira moved back to Portugal where she worked as a Postdoctoral fellow (funded by a FCT project) in Dr. Maria Mota’s lab studying the interplay between iron trafficking and iron regulator proteins in Liver and Blood stage infection of the malaria parasite. Additionally Neide Vieira was focused on clarifying the involvement of the Host’s Ubiquitin proteasome system in plasmodium liver infection, and its potential implication in the initiation of an immune-evasion strategy.
Neide Vieira is currently interested in the interplay between proteostasis and brain aging, and is focused on understanding how defects in protein homeostasis can negatively affect the central nervous system (CNS) and the immune system, influencing cognitive ability.
* Aslani, S., Vieira,N., Marques, F.,Costa, P., Sousa, N. and Palha, J. (2015) " The effect of high fat diet onrat's mood, feeding behavior and response to stress". TranslationalPsychiatry. 5:e684.
* Mota, S.*, Vieira, N.*, Barbosa, S., Delaveau, T., Torchet. C, Le Saux, A., Garcia, M., Pereira, A., Lemoine, S., Coulpier, F., Darzacq, X., Benard, L., Casal, M., Devaux, F. and Paiva, S. (2014) "Role of the DHH1 gene in the regulation of monocarboxylic acids transporters expression in Saccharomyces cerevisiae". PLoS ONE. 9(11):e111589. *Both authors contributed equally to the work. 2012 Impact factor – 3.730.
* Vieira, N.*, Deng, F-M.*, Liang, F-X., Liao, Y., Chang, J., Zhou, G., Zheng, W., Simon,J-P., Ding, M., Wu, X-R., Romih, R., Kreibich, G. and Sun, T-T. (2014) "SNX31: A Novel Sorting Nexin Associated with the Uroplakin-Degrading Multivesicular Bodies in terminally Differentiated Urothelial Cells". PLoS ONE. 9(6):e99644. *Both authors contributed equally to the work. 2012 Impact factor – 3.730.
* Becuwe, M*, Vieira, N.*, Lara, D., Gomes, J., Cunha, C., Haguenauer-Tsapis, R.,Casal, M., Paiva, S. and Léon, S. (2012) “A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis”. J Cell Biol., 196:247-59 *Both authors contributed equally to the work. 2011 Impact factor – 10.264.
* Vieira, N., Casal, M., Johansson, B., MacCallum D., Brown, A. and Paiva, S. (2010) “Functional specialization and differential regulation of short chain carboxylic acid transporters in the pathogen Candida albicans”. Molecular Microbiology, 75:1337-54. 2010 Impact factor – 4.819.
* Vieira, N., Pereira, F., Casal, M., Brown, A.,Paiva, S. and Johansson, B. (2010) “A set of plasmids for in vivo construction of integrative Candida albicans vectors in Saccharomyces cerevisiae”. YEAST, 27:933-9. 2010 Impact factor – 1.626.
* Paiva, S., Vieira, N., Nondier, I., Haguenauer-Tsapis, R., Casal, M. and Urban-Grimal, D. (2009) “Glucose-Induced Ubiquitylation and Endocytosis of the Yeast Jen1 Transporter:role of Ubiquitin-K63 chains”, J Biol Chem, 284:19228-36. 2009 Impact factor – 5.328.
Awards, Fellowships and Grants
2005: Best student of Applied Biology, University of Minho, 2001-2005.
2006: Portuguese Science Foundation (FCT) PhD scholarship.
2006: FEBS Youth Travel Grant. Advanced practical course: From functional genomics to molecular proteomics, September2-13, 2006, in Yerevan, Armenia.
2007: EMBO and FEBS Youth Travel Grant. Workshop on Endocytic Systems: Mechanism and Function, September 18-23, 2007, in Villars-sur-Ollon, Switzerland.
2008: FEBS Youth Travel Grant. Workshop on “Lipids as regulators of cell function” inIsland of Spetses, Greece, June 16-21, 2008.
2009: FEBS Youth Travel Grant. Advanced practical and lecture Course: comparative analysis of in vitro and in vivo Candida albicans-host interaction systems in Madrid, Spain, February 1-14, 2009.
2011: 2nd Poster Award, Vieira, N., Fang-Ming, D., Zhou, G., Wendy, S.,Weiyue, Z. and Tung-Tien, S. “SNX31 mediates endosomal sorting of urothelial-bacterial receptors in the mammalian urothelium”. Center of Excellence in Urological Diseases, March, 2011, New York, USA.
2011: 1st Poster Award by Nature Cell Biology. Becuwe, M*, Vieira, N.*, Lara,D., Gomes, J., Cunha, C., Haguenauer-Tsapis, R., Casal, M., Paiva, S.and Léon, S. “A metabolic on a yeast arrestin connects glucose signalling to transporter endocytosis”. EMBO meeting on Ubiquitin and ubiquitin-like modifiers, September 21-25, 2011, Cavtat, Croatia. *Both authors contributed equally to the work.
2013: Portuguese Science Foundation (FCT) Post-Doc scholarship.