Research & Scientists | Neurosciences | People | NUNOSILVA


Name: Nuno A. Silva

Office: I2.02

School Phone: +351 604 839

Email: nunosilva@med.uminho.pt




Keywords: Spinal Cord Injury Regenerative Medicine


Nuno Silva completed his BSc in Applied Biology in 2007 and received his PhD in Tissue Engineering, Regenerative Medicine and Stem Cells from the University of Minho in 2012. His PhD work consisted on the development of novel approaches for Spinal Cord Injury Repair based on biodegradable materials and stem cells. His PhD was carried out in the 3B’s Research Group, in the Life and Health Sciences Research Institute (ICVS), both from the University of Minho, and in the Centre for Cellular and Biomolecular Research of the University of Toronto.

In 2012 he started a post-doc at the Life and Health Sciences Research Institute dedicated to the development of pharmacological therapies to treat the injured spinal cord.

He is currently an author of 13 papers published in international peer-reviewed journals. Recently, his work published in Biochimie made the front cover of the journal. Finally, he is author of a book chapter and more than 30 abstracts submitted to international conferences, being awarded with the best poster presentation on the 11th Meeting of the Portuguese Society for Neurosciences in 2009 and on the 2nd Meeting of the Portuguese Institute for Biotechnology and Bioengineering.


Hybrid - Templates for Peripheral Nerve Regeneration  

Multidisciplinary Strategies for Spinal Cord Injury Repair  

Selected Publications

Silva NA, Cooke MJ, Tam RY, Sousa N, Salgado AJ, Reis RL, Shoichet MS. The effects of peptide modified gellan gum and olfactory ensheathing glia cells on neural stem/progenitor cell fate. Biomaterials. 2012 Sep;33(27):6345-54. doi: 10.1016/j.biomaterials.2012.05.050. Epub 2012 Jun 12.

Silva NA, Gimble JM, Sousa N, Reis RL, Salgado AJ. Combining Adult Stem Cells and Olfactory Ensheathing Cells: The Secretome Effect. Stem Cells and Development. April 15, 2013, 22(8): 1232-1240. doi:10.1089/scd.2012.0524.

Silva NA, Sousa RA, Pires AO, Sousa N, Salgado AJ, Reis RL. Interactions between Schwann and olfactory ensheathing cells with a starch/polycaprolactone scaffold aimed at spinal cord injury repair. J Biomed Mater Res A. 2011 Nov 29. doi: 10.1002/jbm.a.33289. [Epub ahead of print]

Silva NA, Sousa RA, Fraga JS, Fontes M, Leite-Almeida H, Cerqueira R, Almeida A, Sousa N, Reis Rl, Salgado AJ. Benefits of Spine Stabilization with Biodegradable Scaffolds in Spinal Cord Injured Rats. Tiss Engineer Part C: Methods, 9:101-108 (2013).

Cerqueira SR, Oliveira JM, Silva NA, Leite-Almeida H, Ribeiro-Samy S, Almeida A, Mano JF, Sousa N, Salgado AJ, Reis RL. Microglia Response and In vivo Therapeutic Potential of Methylprednisolone-Loaded Dendrimer Nanoparticles in Spinal Cord Injury. Small, 9(5):738-749 (2013).

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