Research & Scientists | People | JAPALHA


Name: Joana Palha

Office: G2.30

School Phone: +351 253 604 817

Email: japalha@med.uminho.pt




Keywords: Choroid plexus blood-brain barrier cerebrospinal fluid thyroid hormones aging


Joana Palha (PhD, born 1969) is full professor in the medical school, School of Medicine, University of Minho, Braga, Portugal and vice-dean for postgraduate studies.

She is a neuroscientist, with work focused mostly in the barriers of the brain, and in the study of genetic and biochemical determinants of aging and neuropsychiatric disorders.

She presently serves at the IBRO (International Brain Research Organization) and at the SFN (Society for Neurosciences, USA). She has served as a COST Committee of Senior Officials, and as a delegate for the COST Biomedicine and Molecular Biosciences; and was secretary of the Portuguese Society for Neurosciences. She has been part of the jury of several international prizes and committees.

She has reviewed fornational (Portuguese Science Foundation) and international funding agencies (European Commission; National Science Foundation, USA; Alzheimer’s Research Foundation; Fulbright;Research Council, UK).

She is associate editor of Frontiers in Neurosciences, and is reviewer in several journals.

She has published over 90 articles in peered-reviewed journals.


Communication across the barriers (Leader) 

Maintaining health in old age through homeostasis (Switchbox)  


Neural cells modulation and support  

The role of the immune system in mood disorders and cognition  

Selected Publications

Mesquita SD, Ferreira AC, Falcão AM, Sousa JC, Oliveira TG, Correia-Neves M, Sousa N, Marques F, Palha JA. Lipocalin 2 modulates the cellular response to amyloid beta. Cell Death Differ. 2014 May 23. doi: 10.1038/cdd.2014.68. [Epub ahead of print]

Aslani S, Harb MR, Costa PS, Almeida OF, Sousa N, Palha JA. Day and night: diurnal phase influences the response to chronic mild stress. Front Behav Neurosci, 8:82 (2014).

Marques F, Mesquita SD, Sousa JC, Coppola G, Gao F, Geschwind DH, Columba-Cabezas S, Aloisi F, Degn M, Cerqueira JJ, Sousa N, Correia-Neves M, Palha JA. Lipocalin 2 is present in the EAE brain and is modulated by natalizumab.Front Cell Neurosci. 2012 Aug 9;6:33. doi: 10.3389/fncel.2012.00033. eCollection 2012.

Costeira MJ, Oliveira P, Santos NC, Ares S, Saenz-Rico B, de Escobar GM, Palha JA. Psychomotor development of children from an iodine-deficient region. J Pediatr. 2011 Sep;159(3):447-53. doi: 10.1016/j.jpeds.2011.02.034. Epub 2011 Apr 14.

Marques F, Sousa JC, Sousa N, Palha JA. Blood–brain-barriers in aging and in Alzheimer’s disease. Mol Neurodegener, 8:38 (2013).

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