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Research & Scientists | People | VITORPINTO

 

Name: Vitor Pinto

Office: I2.13

School Phone: +351 253 604 875

Email: vitorpinto@med.uminho.pt

 

 

 

Keywords: Electrophysiology Synaptic plasticity Stress Alzheimer

About

Vítor Pinto graduated in Biochemistry by the University of Porto in 2004 and completed a PhD degree in Human Biology by the Porto’s Medical School in 2010.The work developed by Vítor Pinto during his PhD was performed in the Institute for Molecular and Cell Biology, where he specialized in ex-vivo electrophysiological recordings. Soon after the completion of his PhD, Vítor Pinto moved to the Life and Health Science Research Institute. Since then, Vítor Pinto is PI in a project dedicated to the study of synaptic and network malfunctions in Alzheimer’s disease.


Projects

Deciphering the role of Aß and TAU among neuronal subpopulations in Alzheimer´s disease network malfunction. (Leader) 

Characterization of phospholipase D knock-out animal models  

Environmental stress and Alzheimer´s disease pathologies  

Impact of chronic stress on brain spliceosome – implications for neurodegeneration  

Sensomotor mechanisms and Alzheimer´s disease pathology  

The role of brain lipid metabolism in the modulation of chronic stress effects  

Selected Publications

Oliveira TG, Chan RB, Bravo FV, Miranda A, Silva RR, Zhou B, Marques F, Pinto V, Cerqueira JJ, Di Paolo G, Sousa N. The impact of chronic stress on the rat brain lipidome. Mol Psych, 21(1):80-88 (2016).

Lopes S, Vaz-Silva J, Pinto V, Dalla C, Kokras N, Bedenk B, Mack N, Czisch M, Almeida OFX, Sousa N, Sotiropoulos I. Tau protein is essential for stress-induced brain pathology. PNAS USA, 113(26):E3755-E3763 (2016)

Pinto V, Costa JC, Morgado P, Mota C, Miranda A, Bravo FV, Oliveira TG, Cerqueira JJ, Sousa N. Differential impact of chronic stress along the hippocampal dorsal-ventral axis. Brain Struct Funct, in press

Lopes S, Lopes A, Pinto V, Guimarães MR, Sardinha VM, Duarte-Silva S, Pinheiro S, Pizarro J, Oliveira JF, Sousa N, Leite-Almeida H, Sotiropoulos I. Absence of Tau triggers age-dependent sciatic nerve morphofunctional deficits and motor impairment. Aging Cell, 15(2):208-216 (2016)

Ferreira AC, Pinto V, Mesquita SD, Novais A, Sousa JC, Correia-Neves M, Sousa N, Palha JA, Marques F. (2013) Lipocalin-2 is involved in emotional behaviors and cognitive function. Front. Cell. Neurosci. 7:122. doi: 10.3389/fncel.2013.00122

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