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Research & Scientists | Research projects

  MIRD Projects Leaders
Active tuberculosis in diabetic patients: biological basis for the increased susceptibility 
Margarida Correia-Neves
Ammonium toxicity in yeast: different culture conditions with different nitrogen sources 
Cecília Leão
Bovine tuberculosis – One health approach 
Margarida Correia-Neves
Computational Molecular Biology and Evolution of the Mycobacterium tuberculosis Complex 
Nuno S. Osório
Defining redox pathways in antimalarial drug resistance 
Maria Isabel Veiga
Detoxification mechanisms in Plasmodium falciparum malaria 
Maria Isabel Veiga
Development of molecular tools in Paracoccidioides brasiliensis: towards identification and characterization of virulent factors 
Fernando José Santos Rodrigues
Dynamics of granuloma assembling 
Gil Castro
Elucidation of the mechanisms mediating the aging process under caloric restriction 
Belém Sampaio-Marques
Paula Ludovico
Evaluation of autophagy in cell sheets of adipose stromal/stem cells in normoxia and hypoxia: correlation with stemness 
Evaluation of immune-determinants associated with resistance/susceptibility to Paracoccidioides brasiliensis: a mouse model perspective 
Fernando José Santos Rodrigues
Evaluation of the effect of diabetic BM stroma on the progression and chemoresistance of AML 
Paula Ludovico
Functional impact of allelic variants of metabolic genes under positive selection in the fitness of Mycobacterium tuberculosis 
Fernando José Santos Rodrigues
Genetic determinants of malaria resistance in Dominican Republic 
Maria Isabel Veiga
Genetic determinants of TB resistance: the IL-12 family of cytokines 
Gil Castro
Host pathogen interactions in Mycobacterium ulcerans infection - Buruli Ulcer 
Jorge Pedrosa
How the thymus copes with infection? 
Margarida Correia-Neves
Immune reconstitution of HIV patients: the role of regulatory T cells and the thymus 
Margarida Correia-Neves
Innate immunity & Inflammation: impact on the immune response to intracellular pathogens: (M. tuberculosis; Listeria; Klebsiella) 
Gil Castro
Lung development orchestration by tissue macrophages 
Sandra Costa
Modulating bacteriostasis in M. tuberculosis infection: impact of the microbiome 
Egídio Torrado
Nanomedicine/drug delivery systems to treat mycobacteriosis 
Jorge Pedrosa
Pathogen Diversity and Epitope-based Immunoinformatics in Tuberculosis 
Nuno S. Osório
Study on the relationship between aging and autophagy in yeast Saccharomyces cerevisiae 
Paula Ludovico
The interplay between autophagy and DNA replication stress during aging 
Paula Ludovico
The role of LKB1-AMPK pathway on acute myeloid leukemia 
Paula Ludovico
Understanding BCG vaccination: Correlates of protection/pathology following infection with M. tuberculosis 
Egídio Torrado
Weak acid resistance in yeasts: better food preservative conditions and improvement of Saccharomyces cerevisiae fitness for industrial applications  
Cecília Leão
  NERD Projects Leaders
Ataxin-3 and ubiquitin signalling in the nervous system 
Patrícia Maciel
BNST – Bridging aNxiety, Stress and addicTion 
José Miguel Pêgo
Characterization of phospholipase D knock-out animal models 
Tiago Gil Oliveira
Clinical and Genetic studies of human neurodevelopmental disorders 
Patrícia Maciel
Communication across the barriers 
Fernanda Marques
Joana Palha
Cumulative stress: the link between depression and dementia 
Ioannis Sotiropoulos
Deciphering the role of Aß and TAU among neuronal subpopulations in Alzheimer´s disease network malfunction. 
Vitor Pinto
Developing a neurofunctional intervention for emotion regulation under stress 
Pedro Morgado
Environmental stress and Alzheimer´s disease pathologies 
Ioannis Sotiropoulos
Epigenetic regulators of pluripotency and neuronal differentiation and function 
Exploring the Therapeutic Potential of the Secretome of Mesenchymal Stem Cells in CNS Regenerative Medicine 
António Salgado
Genetic and EpiGenetic orchestration of the adult brain neuroplasticity in health and depression 
Luisa Alexandra Meireles Pinto
Hybrid - Templates for Peripheral Nerve Regeneration 
António Salgado
Identification of novel target genes in microsatellite-unstable tumours 
Rui Manuel Vieira Reis
Impact of chronic stress on brain spliceosome – implications for neurodegeneration 
Impact of neurotoxicity on fish central nervous system 
Armando Almeida
Filipa Pinto-Ribeiro
Impact of proliferative, neurogenic and gliogenic modulatory events on the pathophysiology of Depression 
Luisa Alexandra Meireles Pinto
Long term impact of prenatal glucocorticoid exposure (Human study) 
Ana João Rodrigues
Maintaining health in old age through homeostasis (Switchbox) 
Nuno Sousa
Multidisciplinary Strategies for Spinal Cord Injury Repair 
António Salgado
Multiple Sclerosis: Studying lipocalin 2 as a novel player in the pathophysiology of the disease 
Fernanda Marques
MyHealth 
Nuno Sousa
Neural cells modulation and support 
João Carlos Sousa
Neuro-Politics: the neural correlates of political decision-making: an fMRI-based approach 
Patrício Costa
Obsessive-compulsive disorder: focus on stress and decision-making 
Pedro Morgado
Pain modulation in chronic pain syndromes and comorbid mood disorders 
Armando Almeida
Filipa Pinto-Ribeiro
Predictive factors of acute and chronic pain after inguinal hernia repair 
Armando Almeida
Patrícia JR Pinto
Reward circuit: from genes to neurons to behavior 
Ana João Rodrigues
Nuno Sousa
Sensomotor mechanisms and Alzheimer´s disease pathology 
Hugo Almeida
Ioannis Sotiropoulos
Sleep, stress and cognition in a cohort of medical students: an fMRI approach 
Nadine Correia Santos
The role of brain lipid metabolism in the modulation of chronic stress effects 
Tiago Gil Oliveira
The role of the immune system in mood disorders and cognition 
Margarida Correia-Neves
Translating Mechanisms of Aggressiveness in Brain Tumors into Prognostic and Therapeutic Value: Insights from the Oncogenic HOXA9 Homeoprotein 
Bruno Costa
Translation of neuron-astrocyte interactions in complex cognitive functions in health and disease 
João Filipe Oliveira
Treating Refactory Obsessive Compulsive Diroder Using Real-Time Functional Magnetic Resonance Imaging Neurofeedback 
Pedro Morgado
  SURD Projects Leaders
3D Reconstruction of Intestinal Tissue from Capsule Endoscopy Videos by using a Hierarchical Motion Estimation Approach 
Carla Rolanda
Biochemical profile and clinical characteristics of patients with suspected deep venous thrombosis and pulmonary thromboembolism  
Adhemar Longatto
Development of 3D culture systems for in vitro study of tumour pathophysiology 
Fátima Baltazar
Marta Viana-Pereira
Esophageal Regeneration by a Biodegradable Fibrous Mesh Implantion after Endoscopic Submucosal Dissection 
Carla Rolanda
Identification of novel target genes in microsatellite-unstable tumours 
Rui Manuel Vieira Reis
Lung development orchestration by tissue macrophages 
Sandra Costa
Molecularly targeted therapies: mechanisms of resistance 
Olga Martinho
Receptor tyrosine kinases (RTKs): signaling, biologic functions, and potential therapeutic targeting in solid tumors 
Rui Manuel Vieira Reis
Role of human papillomavirus ( HPV ) in non-small cell lung carcinoma (NSCLC ) .  
Adhemar Longatto
Role of Monocarboxylate transporters (MCTs) in cancer 
Fátima Baltazar
Soluble guanylyl cyclase (sGC) stimulators and pulmonary hypertension in CDH 
Cristina Nogueira-Silva
Study center on prevention and early diagnosis of cancer 
Adhemar Longatto
Temporal Control of Cell Differentiation 
The role of Human Papilloma Virus ( HPV ) as the etiologic agent of esophageal cancer 
Adhemar Longatto
Timing lung branching during development 
Rute S Moura
Towards smarter cardiac interventional navigation using MRI-derived personalized models for RT 3D ultrasound interpretation 
Ultra-minimally invasive sentinel limph node (SLN) mapping and excisional biopsy 
Carla Rolanda
  Projects Leaders
Digital Impression System for Dental Prosthesis 
João L. Vilaça
Impact of peripheral neuropathies on CNS function and structure 
Armando Almeida
Hugo Almeida
Importance of Plasmodium falciparum ABC transporters in antimalarial drug resistance  
Maria Isabel Veiga
Innate immunity & Inflammation: impact on the immune response to intracellular pathogens: (M. tuberculosis; Listeria; Klebsiella) 
Pathogenesis and Therapeutics of Machado-Joseph disease 
Patrícia Maciel
Predictive factors of acute and chronic pain after hysterectomy  
Understanding early embryonic T gene – Brachyury - impact in human tumorigenesis 
Rui Manuel Vieira Reis

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