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Researchers from ICVS get further insight on the impact of prenatal stress in the developing brain

Stress perception, response, adaptation, and coping strategies are individually distinct, and the sequel of stress and/or glucocorticoids is also distinct between subjects. Researchers from ICVS have discovered that early life exposure to glucocorticoids program the cholinergic circuit, leading to increased hyper-reactivity to negative stimuli. This programming effect seemed to be restricted to the mesopontine circuitry, hinting that this pathway may be important in setting individual stress v ...

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Prize Melo e Castro on Spinal Cord Injury Research Awarded to an ICVS team

A team from the ICVS was yesterday awarded with the Prize Melo e Castro, from Santa Casa da Misericórdia de Lisboa (SCML), on Spinal Cord Injury (SCI) Research. This award is one of the two Prizes Santa Casa in Neurosciences, which represent an annual investment on neurosciences research of 400,000€, dedicated to two main fields, neurodegenerative diseases and spinal cord injury. The goal of the prize Melo e Castro (200,000€) is to promote new advancements and techniques in SCI ...

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Researchers from the ICVS/3Bs and Hospital de Braga revealed that lipocalin-2 is involved in multiple sclerosis

In a recently published work in Frontiers in Cellular Neuroscience, a team led by Profs Fernanda Marques and João Cerqueira reveals, using an animal model of multiple sclerosis, that lipocalin-2 levels increase in the initial phases of the disease and whenever there is a clinical relapse and decrease upon treatment of symptoms, both in the brain and in the fluid that surrounds it (CSF).  Importantly, they have also shown that lipocalin-2 levels are also elevated in the CSF of multiple ...

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Nuno Sousa was nominated Editor in chief of Frontiers in Behavioral Neuroscience

Nuno Sousa has accepted the invitation to be Editor in chief of "Frontiers in Behavioral Neuroscience", an international journal that has beenc onsolidating as one of the leading journals in the field of behavioral neurosciences. This nomination is the result of the excellent track record of Nuno Sousa in the field of Neurosciences, especially with studies devoted to the understanding of the interactions between brain circuits and complex behavioral outcomes. Nuno Sousa is a Full Profe ...

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Special section in Biochemie Journal: The Mesenchymal Stem Cell secretome in Regenerative Medicine

António Salgado, researcher of the ICVS-3B's, has edited a special section in "Biochemie" Journal.  Biochemie  Special section : The Mesenchymal Stem Cell secretome in Regenerative Medicine Edited by Antonio Salgado and Jeffrey Gimble Volume 95, Issue 12, Pages 2195-2464 (December 2013)  The cover image is from a paper by Nuno Silva, a post-doctoral fellow from ICVS.

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