José Lentilhas-Graça

  • Spinal Cord Injury
  • Neuroimmunology
  • Macrophages
  • Spleen
  • Secretome

José Lentilhas-Graça completed the Bachelor of Science in Basic Studies on Animal Health Sciences in 2009 and the Integrated Masters in Veterinary Medicine in 2010 by the Faculty of Veterinary Medicine of the University of Lisbon. He was a Research Trainee in the Prostate Cancer research field (2014 -2016) at Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine of the University of Lisbon. Currently, José is a PhD student in the Inter-University Doctoral Programme in Ageing and Chronic Disease (PhDOC) (School of Medicine of the University of Minho, Faculty of Medicine of the University of Coimbra and NOVA Medical School|Faculdade de Ciências Médicas of the NOVA University of Lisbon). His research field is Neuroimmunology, studying the therapeutic role of Spleen Macrophages in Spinal Cord Injury and his PhD is carried out at Life and Health Sciences Research Institute (Instituto de Investigação em Ciências da Vida e Saúde, ICVS), School of Medicine, University of Minho, integrated in the ICVS/3B’s Associate Laboratory, and at the Center for Neuroscience and Cell Biology (CNC), University of Coimbra. He published 4 articles in peer review journals, 2 as PhD student.

José Lentilhas-Graça

  • Spinal Cord Injury
  • Neuroimmunology
  • Macrophages
  • Spleen
  • Secretome

José Lentilhas-Graça completed the Bachelor of Science in Basic Studies on Animal Health Sciences in 2009 and the Integrated Masters in Veterinary Medicine in 2010 by the Faculty of Veterinary Medicine of the University of Lisbon. He was a Research Trainee in the Prostate Cancer research field (2014 -2016) at Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine of the University of Lisbon. Currently, José is a PhD student in the Inter-University Doctoral Programme in Ageing and Chronic Disease (PhDOC) (School of Medicine of the University of Minho, Faculty of Medicine of the University of Coimbra and NOVA Medical School|Faculdade de Ciências Médicas of the NOVA University of Lisbon). His research field is Neuroimmunology, studying the therapeutic role of Spleen Macrophages in Spinal Cord Injury and his PhD is carried out at Life and Health Sciences Research Institute (Instituto de Investigação em Ciências da Vida e Saúde, ICVS), School of Medicine, University of Minho, integrated in the ICVS/3B’s Associate Laboratory, and at the Center for Neuroscience and Cell Biology (CNC), University of Coimbra. He published 4 articles in peer review journals, 2 as PhD student.

Scientific Highlights

2022: Pinho, Andreia G.; Cibrão, Jorge R.; Lima, Rui; Gomes, Eduardo D.; Serra, Sofia C.; Lentilhas-Graça, José; Ribeiro, C.; et al. “Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury”. Experimental Neurology. 2022;351:113989.
2020: Monteiro, Susana; Pinho, Andreia G.; Macieira, Mara; Serre-Miranda, Cláudia; Cibrão, Jorge R.; Lima, Rui; Soares-Cunha, Carina; Vasconcelos, Natália L.; Lentilhas-Graça, José; et al. “Splenic sympathetic signaling contributes to acute neutrophil infiltration of the injured spinal cord”. Journal of Neuroinflammation. 2020;17(1);282.
2016: Fundação para a Ciência e a Tecnologia (FCT) PhD fellowship at Life and Health Sciences Research Institute (ICVS), School of Medicine of the University of Minho, integrated in the ICVS/3B’s Associate Laboratory and Faculty of Medicine of the University of Coimbra, in Inter-University Doctoral Programme in Ageing and Chronic Disease (PhDOC).

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Projects

As Leader

Projects

As Member

Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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Molecular Therapies

The remarkable advances in molecular biology in the past decades have led to a better understanding of the mechanisms implicated in the pathophysiology of many CNS disorders as well as mechanisms that control axonal regeneration…

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