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Name: João Carlos Sousa

Office: G2.24

School Phone: +351 253 604 848

Email: jcsousa@med.uminho.pt

 

 

 

Keywords: modulation of neural cells subventricular zone choroid plexus development neural cells extracellular matrix

About

João Carlos Sousa (PhD) is an Assistant Professor in the medical school, School of Medicine, University of Minho, Braga, Portugal. 

He is a neuroscientist who did his PhD in Neuroendocrinology of thyroid hormones, namely how a carrier protein of thyroid hormones (transthyretin) influences behaviour. He then did his post-doctoral training in the neurobiology of stress and later in the role of the epithelial cells of the choroid plexus in the modulation of cerebrospinal fluid content.

He currently is interested in understanding how the external milieu modulates neural progenitor cells proliferation and differentiation by using the subventricular zone, the cerebrospinal fluid and choroid plexus as an interface model between the periphery and the central nervous system. He also is interested in understanding how the extracellular matrix influences cell-cell communication in neural cells during development.

He has published 24 articles in peer-reviewed journals.
He has reviewed for international journals (Neuroscience, PLoSOne, FEBS Journal, Frontiers in Neuroscience).

Projects

Neural cells modulation and support (Leader) 

Communication across the barriers  

Selected Publications

Dias-Ferreira E, Sousa JC, Melo I, Morgado P, Mesquita AR, Cerqueira JJ, Costa RM, Sousa N. Chronic stress causes frontostriatal reorganization and affects decision-making. Science. 2009 Jul 31;325(5940):621-5. doi: 10.1126/science.1171203.

Novais A, Ferreira AC, Marques F, Pego JM, Cerqueira JJ, David-Pereira A, Campos FL, Dalla C, Kokras N, Sousa N, Palha JA, Sousa JC. Neudesin is involved in anxiety behavior: structural and neurochemical correlates. Front Behav Neurosci, 7:119 (2013).

Falcão AM, Marques F, Novais A, Sousa N, Palha JA, Sousa JC. The path from the choroid plexus to the subventricular zone: go with the flow! Front Cell Neurosci. 2012 Aug 9;6:34. doi: 10.3389/fncel.2012.00034. eCollection 2012.

Falcão AM, Palha JA, Ferreira AC, Marques F, Sousa N, Sousa JC. Topographical analysis of the subependymal zone neurogenic niche. PLoS One. 2012;7(6):e38647. doi: 10.1371/journal.pone.0038647. Epub 2012 Jun 20.

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