Andreia Monteiro

  • Neuroimmunology
  • Neurotrauma
  • Neuroregeneration
  • Spinal Cord Injury
  • Macrophages

Andreia Monteiro has been a Fellowship Researcher in the ReNEU team at the Life and Health Sciences Research Institute (ICVS) – University of Minho since 2021. She completed her master’s in Biochemistry in 2020 at the Faculty of Sciences and School of Medicine and Biomedical Sciences, University of Porto. Her M. Sc work focused on the role of adenosine A2A receptors in invasive group B Streptococcus disease in newborns and in establishing an invasive GBS model in elderly mice. Her scientific training also involves a 4-month voluntary work at the former laboratory of Sandra Costa at the Life and Health Sciences Research Institute (ICVS)- University of Minho. There, she learned how lung macrophages could mediate lung differentiation and regeneration in acute lung injury and idiopathic pulmonary fibrosis. Her research interests are focused on 1) understanding how biological sex affects the immune response to CNS injury and repair, 2) identification of immunomodulatory targets and validating them in translational/clinical studies, and 3) development of combinatory approaches for CNS protection and regeneration.

Andreia Monteiro

  • Neuroimmunology
  • Neurotrauma
  • Neuroregeneration
  • Spinal Cord Injury
  • Macrophages

Andreia Monteiro has been a Fellowship Researcher in the ReNEU team at the Life and Health Sciences Research Institute (ICVS) – University of Minho since 2021. She completed her master’s in Biochemistry in 2020 at the Faculty of Sciences and School of Medicine and Biomedical Sciences, University of Porto. Her M. Sc work focused on the role of adenosine A2A receptors in invasive group B Streptococcus disease in newborns and in establishing an invasive GBS model in elderly mice. Her scientific training also involves a 4-month voluntary work at the former laboratory of Sandra Costa at the Life and Health Sciences Research Institute (ICVS)- University of Minho. There, she learned how lung macrophages could mediate lung differentiation and regeneration in acute lung injury and idiopathic pulmonary fibrosis. Her research interests are focused on 1) understanding how biological sex affects the immune response to CNS injury and repair, 2) identification of immunomodulatory targets and validating them in translational/clinical studies, and 3) development of combinatory approaches for CNS protection and regeneration.

Scientific Highlights

Lima R, Monteiro A, Salgado AJ, Monteiro S, Silva NA. Pathophysiology and Therapeutic Approaches for Spinal Cord Injury. Int J Mol Sci. 2022 Nov 10;23(22):13833. doi: 10.3390/ijms232213833.

Pinho AG, Monteiro A, Fernandes S, de Sousa N, Salgado AJ, Silva NA, Monteiro S. The Central Nervous System Source Modulates Microglia Function and Morphology In Vitro. Int J Mol Sci. 2023 Apr 22;24(9):7685. doi: 10.3390/ijms24097685.

Lentilhas-Graça, José; Santos, Diogo J.; Afonso, João; Monteiro, Andreia; Pinho, Andreia G.; Mendes, Vera M.; Dias, Marta S.; et al. “The secretome of macrophages has a differential impact on spinal cord injury recovery according to the polarization protocol”. Frontiers in Immunology 15 (2024): http://dx.doi. org/10.3389/fimmu.2024.1354479.

Maria M. Moura; Monteiro, Andreia; António J. Salgado; Nuno A. Silva; Monteiro, Susana. “Disrupted Autonomic Pathways in Spinal Cord Injury: Implications for the Immune Regulation”. Neurobiology of Disease (2024): https://doi.org/10. 1016/j.nbd.2024.106500.

Sousa, Carla S.; Monteiro, Andreia; Salgado, António J.; Silva, Nuno A.. “Combinatorial therapies for spinal cord injury repair”. Neural Regeneration Research (2024): http://dx.doi.org/10.4103/nrr.nrr-d-24-00061.

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Projects

As Leader

Projects

As Member

Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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Molecular Therapies

The remarkable advances in molecular biology in the past decades have led to a better understanding of the mechanisms implicated in the pathophysiology of many CNS disorders as well as mechanisms that control axonal regeneration…

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