André Mira

  • Neuroregeneration
  • Neuroimmunology
  • Spinal Cord Injury
  • Pharmacological Therapy
  • Epidural Electrical Stimulation

André Vidinha-Mira completed his graduation in Human Biology in 2019/07 at Évora’s University. During his graduation, he perfomed an internship on the subject of Optogenetics in a Drosophila melanogaster model at CEDOC (Chronic Diseases Research Centre), in Lisbon, under the supervision of Doctor César Mendes. He completed his Master Course in Neurobiology in 2021/10 at Porto’s University. His master thesis was supervised by Doctor Andreia Teixeira-Castro at Minho’s University – ICVS (Life and Health Sciences Research Institute), with the subjet being to study the Impact of Serotonergic Signalling in Neurodegeneration, in which he worked with mice and developed a deep know-how of behavioural tests.

In 2022/07 he joined the ReNeu team in ICVS focused in Neural Trauma and Nervous System Regenerative Medicine as a Research Fellow, supervised by Doctor Nídia de Sousa, where he deepened his know-how on molecular and histological tissue analysis. He then worked as a Research Fellow, supervised by Doctor Nuno Silva, where he deepened his know-how in in vitro models and electrical stimulation studies. Since 2025/02 he now is a PhD student under the supervision of Dr. Nuno Silva. During his time at ICVS, André participated in 12 scientific posters, having presented 4 as main author, winning a best poster presentation award with one of them. He also participated in the data collection and writing of 6 journal articles.

André Mira

  • Neuroregeneration
  • Neuroimmunology
  • Spinal Cord Injury
  • Pharmacological Therapy
  • Epidural Electrical Stimulation

André Vidinha-Mira completed his graduation in Human Biology in 2019/07 at Évora’s University. During his graduation, he perfomed an internship on the subject of Optogenetics in a Drosophila melanogaster model at CEDOC (Chronic Diseases Research Centre), in Lisbon, under the supervision of Doctor César Mendes. He completed his Master Course in Neurobiology in 2021/10 at Porto’s University. His master thesis was supervised by Doctor Andreia Teixeira-Castro at Minho’s University – ICVS (Life and Health Sciences Research Institute), with the subjet being to study the Impact of Serotonergic Signalling in Neurodegeneration, in which he worked with mice and developed a deep know-how of behavioural tests.

In 2022/07 he joined the ReNeu team in ICVS focused in Neural Trauma and Nervous System Regenerative Medicine as a Research Fellow, supervised by Doctor Nídia de Sousa, where he deepened his know-how on molecular and histological tissue analysis. He then worked as a Research Fellow, supervised by Doctor Nuno Silva, where he deepened his know-how in in vitro models and electrical stimulation studies. Since 2025/02 he now is a PhD student under the supervision of Dr. Nuno Silva. During his time at ICVS, André participated in 12 scientific posters, having presented 4 as main author, winning a best poster presentation award with one of them. He also participated in the data collection and writing of 6 journal articles.

Scientific Highlights

Best Poster Presentation Award – YES Meeting 2021

Ferreira-Lomba, B., Guerreiro, S., Cunha-Garcia, D., Pereira-Sousa, J., Duarte-Silva, S., Teixeira-Castro, A., Kleven, MS., Vilasboas-Campos, D., Vidinha-Mira, A., Newman-Tancredi, A., & Maciel, P. (2022). Befiradol treatment ameliorated the motor dysfunction of Spinocerebellar Ataxia Type 3 mouse model. Neuroscience Applied, Volume 1, Supplement 2. https://doi.org/10.1016/j.nsa.2022.100835

de Sousa, N., Correia-Silva, A., Pinho, A. G., Vidinha-Mira, A., Cainé, L., Lima, M. F., Santos, D. J., Cibrão, J. R., Campos, J., Cavaleiro, H., Pinho, T. S., Afonso, J. L., Sampaio-Marques, B., Monteiro, S., Silva, N. A., Barreiro-Iglesias, A., & Salgado, A. J. (2025). Baclofen modulates the immune response after spinal cord injury with locomotor benefits. British journal of pharmacology, 182(8), 1783–1802. https://doi.org/10.1111/bph.17438
Cibrão, J. R., Armada, M., Lima, M. F., Vidinha-Mira, A., Campos, J., Pinho, T. S., Salgado, A. J., Ainla, A., & Silva, N. A. (2025). Development and application of a novel multi-channel in vitro electrical stimulator for cellular research. BMC biomedical engineering, 7(1), 3. https://doi.org/10.1186/s42490-025-00090-8
Cunha-Garcia, D., Ferreira-Lomba, B, Guerreiro, S., Vidinha-Mira, A., Monteiro-Fernandes, D., Varney, MA., Kleven, MS., Maciel, P., Teixeira-Castro, A., Duarte-Silva, S., & Newman-Tancredi. A. (2025). The 5-HT1A receptor agonist NLX-112 rescues motor swimming deficits in Spinocerebellar Ataxia type 3 mice. bioRxiv 2025.09.04.674027; doi: https://doi.org/10.1101/2025.09.04.674027
Ferreira-Lomba, B., Guerreiro, S., Duarte-Silva, S., Cunha-Garcia, D., Oliveira, S., Vieira, C., Pereira-Sousa, J., Vilasboas-Campos, D., Vidinha-Mira, A., Monteiro-Fernandes, D., Varney, MA., Kleven, MS., Newman-Tancredi, A., Teixeira-Castro, A., Maciel, P. (2025). Efficacy of chronic 5-HT1A receptor agonism by NLX-112 in a mouse model of Spinocerebellar Ataxia type 3. bioRxiv 2025.08.21.671624; doi: https://doi.org/10.1101/2025.08.21.671624

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Projects

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Projects

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Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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Molecular Therapies

The remarkable advances in molecular biology in the past decades have led to a better understanding of the mechanisms implicated in the pathophysiology of many CNS disorders as well as mechanisms that control axonal regeneration…

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