Andreia G. Pinho

  • Microglia
  • Neutrophils
  • Neuroimmunology
  • Spinal cord Injury

Andreia Pinho is a PhD student in ReNEU team at the Life and Health Sciences Research Institute (ICVS) – University of Minho. She completed her Biochemistry degree in 2017 (Faculty of Sciences, University of Porto) and her MSc in Health Sciences in 2019 (School of Medicine, University of Minho). During her scientific path she was involved in projects from basic to applied research sciences where she was able to study, optimize and perform in vitro to in vivo analysis. Thus, on i3S she studied the requirement of an upstream sequence element (a non-coding region of our DNA) in the regulation of protein expression whereas on ICVS she dissect the therapeutic value of stem cells secretome (a cocktail of biofactors secreted by these cells) as a whole versus it’s individual proteic or vesicular fraction in Spinal Cord Injury (SCI) context. While dissecting the secretome therapeutic effect she met microglia cells which caught her attention. For this reason, she enrolled in a PhD to further dissect the neuroinflammation contribution to SCI pathophysiology. Therefore, her main focus is to dissect microglia-neutrophil interaction in SCI, exploring how neutrophils as peripheral immune cells shape microglia behavior and local inflammation.

Scientific Highlights

2022: Andreia G. Pinho*, Jorge R. Cibrão*, Rui Lima, et al., Immunomodulatory and regenerative effects of the full and fractioned adipose tissue derived stem cells secretome in spinal cord injury, Experimental Neurology 2021: EMBO Fee Waiver for the upcoming virtual EMBO Workshop Microglia 2021 2021: FCT PhD fellowship at Life and Health Sciences Research Institute (ICVS), School of Medicine – University of Minho 2020: Pinho G, Andreia*, Cibrão, Jorge*; Silva, Nuno A; Monteiro, Susana; Salgado, António J. Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders. Pharmaceuticals


Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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