Belém Sampaio-Marques

  • Parkinson's disease
  • Secretome
  • Stem cells
  • Disease modeling
  • Parkinson's disease models

Belém Sampaio Marques graduated in Biology from the University of the Azores in 2003 and obtained a Ph.D. in Health Sciences from the University of Minho in 2012. Between 2013 and 2019, she developed postdoctoral studies on the study and elucidation of mechanisms related to aging and age-related diseases, using the yeast Saccharomyces cerevisiae as a model for neurodegenerative diseases, namely Parkinson’s disease. Since 2019, she has been working as a Junior Researcher at ICVS and also serves as an Assistant Professor at the School of Medicine, University of Minho. Her research focuses on elucidating the molecular mechanisms and cellular processes of aging and age-related diseases. As of June 2023, she has shifted her research focus towards developing models to study Parkinson’s disease and exploring the role of the secretome of mesenchymal stem cells (MSCs) in neuroprotection and repair. Her track record is currently reflected in 48 publications in international peer-reviewed journals (>2200 citations and h-index=20) and 2 book chapters. She has supervised 1 PhD and 5 MSc students. She has served as ad hoc reviewer for more than 20 journals and some funding agencies.

Belém Sampaio-Marques

  • Parkinson's disease
  • Secretome
  • Stem cells
  • Disease modeling
  • Parkinson's disease models

Belém Sampaio Marques graduated in Biology from the University of the Azores in 2003 and obtained a Ph.D. in Health Sciences from the University of Minho in 2012. Between 2013 and 2019, she developed postdoctoral studies on the study and elucidation of mechanisms related to aging and age-related diseases, using the yeast Saccharomyces cerevisiae as a model for neurodegenerative diseases, namely Parkinson’s disease. Since 2019, she has been working as a Junior Researcher at ICVS and also serves as an Assistant Professor at the School of Medicine, University of Minho. Her research focuses on elucidating the molecular mechanisms and cellular processes of aging and age-related diseases. As of June 2023, she has shifted her research focus towards developing models to study Parkinson’s disease and exploring the role of the secretome of mesenchymal stem cells (MSCs) in neuroprotection and repair. Her track record is currently reflected in 48 publications in international peer-reviewed journals (>2200 citations and h-index=20) and 2 book chapters. She has supervised 1 PhD and 5 MSc students. She has served as ad hoc reviewer for more than 20 journals and some funding agencies.

Scientific Highlights

2023: Silva et al., J Clin Med., 26;12(11):3699.

2021:  Klionsky et al., Autophagy, 17(1):1-382

2019: Sampaio-Marques B. Aging Cell.;18(4):e12922.

2017: Guedes et al., Mech Ageing Dev.; 161(Pt B):270-276.

2017: Prize of 5K in the 1º INL-ICVS Hackathon

2013: Young Scientist Prize –Tribute to Isabel Spencer-Martins – From Portuguese Society of Microbiology

 

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Projects

As Leader

Projects

As Member

Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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Enabling Technologies in CNS Repair

Recent advances in the field of electronics, miniaturisation and microfabrication and a deeper understanding of the interface between physics and living matter for sensing and neural stimulation allow us to develop new…

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Molecular Therapies

The remarkable advances in molecular biology in the past decades have led to a better understanding of the mechanisms implicated in the pathophysiology of many CNS disorders as well as mechanisms that control axonal regeneration…

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