Belém Sampaio Marques graduated in Biology from the University of the Azores in 2003 and obtained a Ph.D. in Health Sciences from the University of Minho in 2012. Between 2013 and 2019, she developed postdoctoral studies on the study and elucidation of mechanisms related to aging and age-related diseases, using the yeast Saccharomyces cerevisiae as a model for neurodegenerative diseases, namely Parkinson’s disease. Since 2019, she has been working as a Junior Researcher at ICVS and also serves as an Assistant Professor at the School of Medicine, University of Minho. Her research focuses on elucidating the molecular mechanisms and cellular processes of aging and age-related diseases. As of June 2023, she has shifted her research focus towards developing models to study Parkinson’s disease and exploring the role of the secretome of mesenchymal stem cells (MSCs) in neuroprotection and repair. Her track record is currently reflected in 48 publications in international peer-reviewed journals (>2200 citations and h-index=20) and 2 book chapters. She has supervised 1 PhD and 5 MSc students. She has served as ad hoc reviewer for more than 20 journals and some funding agencies.
Belém Sampaio Marques graduated in Biology from the University of the Azores in 2003 and obtained a Ph.D. in Health Sciences from the University of Minho in 2012. Between 2013 and 2019, she developed postdoctoral studies on the study and elucidation of mechanisms related to aging and age-related diseases, using the yeast Saccharomyces cerevisiae as a model for neurodegenerative diseases, namely Parkinson’s disease. Since 2019, she has been working as a Junior Researcher at ICVS and also serves as an Assistant Professor at the School of Medicine, University of Minho. Her research focuses on elucidating the molecular mechanisms and cellular processes of aging and age-related diseases. As of June 2023, she has shifted her research focus towards developing models to study Parkinson’s disease and exploring the role of the secretome of mesenchymal stem cells (MSCs) in neuroprotection and repair. Her track record is currently reflected in 48 publications in international peer-reviewed journals (>2200 citations and h-index=20) and 2 book chapters. She has supervised 1 PhD and 5 MSc students. She has served as ad hoc reviewer for more than 20 journals and some funding agencies.
PUBLICATIONS
– Silva AI, Direito M, Pinto-Ribeiro F, Ludovico P, Sampaio-Marques B. Effects of Intermittent Fasting on Regulation of Metabolic Homeostasis: A Systematic Review and Meta-Analysis in Health and Metabolic-Related Disorders. J Clin Med. 2023 May 26;12(11):3699. doi: 10.3390/jcm12113699.
Klionsky DJ, Abdel-Aziz AK, … Sampaio-Marques B… et al., Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280.
Sampaio-Marques B, Guedes A, Vasilevskiy I, Gonçalves S, Outeiro TF, Winderickx J, Burhans WC, Ludovico P. α-Synuclein toxicity in yeast and human cells is caused by cell cycle re-entry and autophagy degradation of ribonucleotide reductase 1. Aging Cell. 2019 Aug;18(4):e12922. doi: 10.1111/acel.12922.
Sampaio-Marques B, Felgueiras C, Silva A, Rodrigues M, Tenreiro S, Franssens V, Reichert AS, Outeiro TF, Winderickx J and Ludovico P. SNCA (a-synuclein)-induced toxicity in yeast cells is dependent on sirtuin2 (Sir2)-mediated mitophagy. Autophagy. 2012, 8(10):1494-509. Doi: 10.4161/auto.21275.
AWARDS
1º INL-ICVS Hackathon – prize of 5 K € with the project: “On-chip selection of exosomal vectors for neurodegenerative diseases treatment” (2017).
Prémio Curso Young Investigator with the course “Autophagy in health and disease: conceptual and methodological advances” ICVS, Escola de Ciências da Saúde (2014).
Young Scientist Prize – SPM Tribute to Isabel Spencer-Martins – 2013.
We have previously validated the use of the secretome of Mesenchymal Stem Cells (MSCs) from different sources, including those derived from pluripotent stem cells (iMSCs), as a possible therapeutic tool in animal…
Phone: +351 253 604 967
Fax: +351 253 604 809
Email: icvs.sec@med.uminho.pt
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
Copyright ©2022 ICVS. All Rights Reserved
Copyright ©2022 ICVS. All Rights Reserved
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
Copyright ©2022 ICVS. All Rights Reserved
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
