Inês Castro

  • Spinal Cord Injury
  • Immune System
  • Spleen
  • Sympathetic Signals
  • TRPV4

Inês Castro earned her BSc in Biochemistry from the University of Minho (2023) and is presently persuing her MSc in Health Sciences at the School of Medicine, University of Minho. Currently, she is developing her master’s thesis entitled “Exploring TRPV4 as a molecular mechanism driving inflammatory cells’ infiltration into the spinal cord after injury” at ICVS under the supervision of Susana Monteiro and Nuno Silva. Inês’s thesis focuses on understanding how TRPV4 is activated in spleen myeloid cells, exploring its role in their activation and in spinal neuroinflammation, and evaluating how the pharmacological modulation of TRPV4 affects recovery after spinal cord injury (SCI). Moreover, this work aims to enhance the understanding of the impact of a peripheral organ in neuroinflammation and to better comprehend the role of myeloid cells in central nervous system (CNS) inflammation and tissue.

Inês Castro

  • Spinal Cord Injury
  • Immune System
  • Spleen
  • Sympathetic Signals
  • TRPV4

Inês Castro earned her BSc in Biochemistry from the University of Minho (2023) and is presently persuing her MSc in Health Sciences at the School of Medicine, University of Minho. Currently, she is developing her master’s thesis entitled “Exploring TRPV4 as a molecular mechanism driving inflammatory cells’ infiltration into the spinal cord after injury” at ICVS under the supervision of Susana Monteiro and Nuno Silva. Inês’s thesis focuses on understanding how TRPV4 is activated in spleen myeloid cells, exploring its role in their activation and in spinal neuroinflammation, and evaluating how the pharmacological modulation of TRPV4 affects recovery after spinal cord injury (SCI). Moreover, this work aims to enhance the understanding of the impact of a peripheral organ in neuroinflammation and to better comprehend the role of myeloid cells in central nervous system (CNS) inflammation and tissue.

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Projects

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Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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