Inês Castro

  • Spinal Cord Injury
  • Immune System
  • Spleen
  • Sympathetic Signals
  • TRPV4

I earned my BSc in Biochemistry at the School of Sciences, University of Minho, and completed my MSc in Health Sciences at the School of Medicine, University of Minho. My master’s thesis, developed at ICVS, focused on exploring TRPV4 as a molecular mechanism driving inflammatory cells’ infiltration into the spinal cord after injury. I characterized TRPV4 expression dynamics in splenic myeloid cells after spinal cord injury and assessed its role in the modulation of peripheral immune responses and myeloid trafficking to the injured spinal cord. Currently, I am interested in better understanding the biomechanical mechanisms through which neural signaling in the spleen, via a TRPV4-dependent pathway, regulates the mobilization of immune cells to the injured spinal cord

Inês Castro

  • Spinal Cord Injury
  • Immune System
  • Spleen
  • Sympathetic Signals
  • TRPV4

I earned my BSc in Biochemistry at the School of Sciences, University of Minho, and completed my MSc in Health Sciences at the School of Medicine, University of Minho. My master’s thesis, developed at ICVS, focused on exploring TRPV4 as a molecular mechanism driving inflammatory cells’ infiltration into the spinal cord after injury. I characterized TRPV4 expression dynamics in splenic myeloid cells after spinal cord injury and assessed its role in the modulation of peripheral immune responses and myeloid trafficking to the injured spinal cord. Currently, I am interested in better understanding the biomechanical mechanisms through which neural signaling in the spleen, via a TRPV4-dependent pathway, regulates the mobilization of immune cells to the injured spinal cord

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Projects

As Leader

Projects

As Member

Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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