Rute S Moura

  • lung development
  • branching morphogenesis
  • chicken embryo
  • in ovo model
  • signaling pathways
  • metabolism

Rute Moura holds a degree in Biochemistry from the University of Porto and a Ph.D. in Biological Sciences from the University of León, Spain. She has more than 15 years of experience as a researcher in the Health Sciences field. Rute currently serves as the Coordinator of the Laboratory Unit, assuming the role of Laboratory Manager to oversee day-to-day operations at ICVS. Her responsibilities encompass the supervision of equipment and procedures, as well as the management of scientific and technical staff. Rute also holds the senior staff position supervising the Histology and Molecular Biology Services Lab, where she undertakes the coordination, monitoring, and support of all aspects related to these facilities. Beyond her management roles, Rute is an Affiliated Researcher of the Surgical Sciences and Allied Technologies Team. In this capacity, she collaborates in projects focused on lung development, utilizing the chicken embryo as a model system.

Rute S Moura

  • lung development
  • branching morphogenesis
  • chicken embryo
  • in ovo model
  • signaling pathways
  • metabolism

Rute Moura holds a degree in Biochemistry from the University of Porto and a Ph.D. in Biological Sciences from the University of León, Spain. She has more than 15 years of experience as a researcher in the Health Sciences field. Rute currently serves as the Coordinator of the Laboratory Unit, assuming the role of Laboratory Manager to oversee day-to-day operations at ICVS. Her responsibilities encompass the supervision of equipment and procedures, as well as the management of scientific and technical staff. Rute also holds the senior staff position supervising the Histology and Molecular Biology Services Lab, where she undertakes the coordination, monitoring, and support of all aspects related to these facilities. Beyond her management roles, Rute is an Affiliated Researcher of the Surgical Sciences and Allied Technologies Team. In this capacity, she collaborates in projects focused on lung development, utilizing the chicken embryo as a model system.

Scientific Highlights

2024. Fernandes-Silva H, Alves MG, Garcez MR, Correia-Pinto J, Oliveira PF, Homem CCF, Moura RS. Retinoic Acid-Mediated Control of Energy Metabolism Is Essential for Lung Branching Morphogenesis. Int J Mol Sci. 2024. doi: 10.3390/ijms25095054
2023. Silva-Ribeiro T, Coelho E, Genisheva Z, Oliveira JM, Correia-Pinto J, Sampaio P, Moura RS. Comparative study of e-cigarette aerosol and cigarette smoke effect on ex vivo embryonic chick lung explants. Toxicol Lett. doi:10.1016/j.toxlet.2023.01.002
2022. Barbosa VB, Costa-Silva PF, Araújo-Silva H, Miranda G, Correia-Pinto J, Moura RS. Molecular insights of Hippo signaling in the chick developing lung. Biochim Biophys Acta Gene Regul Mech. 1866(1):194904. doi:10.1016/j.bbagrm.2022.194904
2021. Caldeira I, Fernandes-Silva H, Machado-Costa D, Correia-Pinto J, Moura RS. Developmental Pathways Underlying Lung Development and Congenital Lung Disorders. Cells 10(11):2987. doi: 10.3390/cells1011298
2021. Fernandes-Silva H, Alves MG, Araújo-Silva H, Silva AM, Correia-Pinto J, Oliveira PF, Moura RS. Lung branching morphogenesis is accompanied by temporal metabolic changes towards a glycolytic preference. Cell Biosci 11:134. doi:10.1186/s13578-021-00654-w
2020. Fernandes-Silva H, Araújo-Silva H, Correia-Pinto J, Moura RS. Retinoic Acid: A Key Regulator of Lung Development. Biomolecules, 10(1):152. doi:10.3390/biom10010152
2019. Moura RS. “Retinoic Acid as a Modulator of Proximal-Distal Patterning and Branching Morphogenesis of the Avian Lung”” in Retinoid and Rexinoid Signaling: Methods and Protocols. Methods in Molecular Biology. Ray SK (Ed), Springer Nature. Chap 15, 209-224. doi:10.1007/978-1-4939-9585-1_15.
2017. Fernandes-Silva H, Vaz-Cunha P, Barbosa VB, Silva-Gonçalves C, Correia-Pinto J, Moura RS. Retinoic acid regulates avian lung branching through a molecular network. Cell Mol Life Sci, 74(24):4599-4619. doi:10.1007/s00018-017-2600-3.
2017. Fernandes-Silva H, Correia-Pinto J, Moura RS. Canonical Sonic Hedgehog Signaling in Early Lung Development. J Dev Biol. 5(1):3. doi:10.3390/jdb5010003
2017. Moura RS, Correia-Pinto J. “”Molecular aspects of avian lung development”” in The Biology of the Avian Respiratory System: Evolution, Development, Structure and Function. Maina JN (Ed); Springer International Publishing. Chap 5, 129-146. doi:10.1007/978-3-319-44153-5_5.

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