Sandra Barata-Antunes

  • Nanotherapeutics
  • Stem Cells
  • Secretome
  • Parkinson's Disease

Sandra Barata Antunes completed her MSc in Biomedical Science from the University of Beira Interior in 2016. Her MSc work consisted in the study of the role of histamine on the modulation of hippocampal inflammation and neurogenesis in adult mice. Currently, she is finishing her PhD in Applied Health Sciences at Life and Health Sciences Research Institute (ICVS, School of Medicine, University of Minho) and in collaboration with International Iberian Nanotechnology Laboratory (INL). Her research work is focused on the development of nanosystems for the delivery of cellular secretome in the context of Parkinson’s Disease. She has also collaborated in other projects in the field of Neurosciences, enrolled in a multidisciplinary team, which resulted in papers published in international peer-reviewed journals.

Sandra Barata-Antunes

  • Nanotherapeutics
  • Stem Cells
  • Secretome
  • Parkinson's Disease

Sandra Barata Antunes completed her MSc in Biomedical Science from the University of Beira Interior in 2016. Her MSc work consisted in the study of the role of histamine on the modulation of hippocampal inflammation and neurogenesis in adult mice. Currently, she is finishing her PhD in Applied Health Sciences at Life and Health Sciences Research Institute (ICVS, School of Medicine, University of Minho) and in collaboration with International Iberian Nanotechnology Laboratory (INL). Her research work is focused on the development of nanosystems for the delivery of cellular secretome in the context of Parkinson’s Disease. She has also collaborated in other projects in the field of Neurosciences, enrolled in a multidisciplinary team, which resulted in papers published in international peer-reviewed journals.

Scientific Highlights

Mendes-Pinheiro, B., Campos, J., Marote, A., Soares-Cunha, C., Nickels, S. L., Monzel, A. S., Cibrão J.R., Loureiro-Campos E., Serra S.C., Barata-Antunes S. et al. (2023). “Treating Parkinson’s Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Administration”. Cells, 12(21), 2565.

Fernandes, A. M., Campos, J., Silva, D., Barata Antunes, S., Lima, R. et al. (2022). “Cerebral Organoids to Study Central Mechanisms of Pain: The Effect of Stem Cell Secretome on Opioid Receptors and Neuroplasticity”. Stem Cells and Development. 641-657.http://doi.org/10.1089/scd.2022.0116.

Mendes-Pinheiro, B., Soares-Cunha, C., Marote, A., Loureiro-Campos, E., Campos, J., Barata-Antunes, S. et al. (2021). “Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: ACloser Look into Non-Motor Phenotype and Glial Response”. InternationalJournal of Molecular Sciences (22)21, 11530. https://doi.org/10.3390/ijms222111530.

Barata-Antunes, S., Teixeira, F. G., Mendes-Pinheiro, B., Domingues, A. V., Vilaça-Faria, H. et al. (2020). “Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson’s Disease”. International Journal of Molecular Sciences (21)10: 3459-3459. https://doi.org/10.3390/ijms21103459.

Saraiva C.*, Barata-Antunes S.*, Santos T., Ferreiro E., Cristóvão AC., Serra-Almeida C., Ferreira R., Bernardino L. (2019). “Histamine modulates hippocampal inflammation and neurogenesis in adult mice”. Scientific Reports; Volume 9, Issue 1, Pages 1-12.
*Both authors contributed equally.

Winner of the best poster communication in the “I Symposium in Applied Biochemistry” at the University of Minho (Braga, Portugal, 2017)

Barata-Antunes S.*, Cristóvão A.C.*, Pires J., Rocha M.S., Bernardino L. (2017). “Dual role of histamine on microglia-induced neurodegeneration”. BBA-Molecular Basis of Disease. Volume 1863, Issue 3, Pages 764–769.

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