Sara Rito Fernandes

  • Spinal cord injury
  • sex differences
  • sympathetic signaling
  • immune response
  • neuroimmunology

Sara Rito Fernandes completed her BSc in Biochemistry (2022) and is presently pursuing her MSc degree in Health Sciences at the School of Medicine, University of Minho. Her Bachelor’s thesis was developed in ICVS, studying the effect of Neutrophils on Microglia after a Spinal Cord Injury, a field in which she continues to work. She is being supervised by Nuno Silva and Susana Monteiro, in a master project entitled “Sex differences in the sympathetic regulation of the immune response and functional recovery after Spinal Cord Injury”. The main goal of this dissertation is to fill an important research gap in the SCI field, by understanding how sexual dimorphism in sympathetic signaling affects SCI’s immune response, inflammation, and pathophysiology. The knowledge gathered is expected to be preponderant for future research dedicated to designing personalized therapies that take into account the specificities of each sex, improving the validity and translational potential of preclinical findings.

Sara Rito Fernandes

  • Spinal cord injury
  • sex differences
  • sympathetic signaling
  • immune response
  • neuroimmunology

Sara Rito Fernandes completed her BSc in Biochemistry (2022) and is presently pursuing her MSc degree in Health Sciences at the School of Medicine, University of Minho. Her Bachelor’s thesis was developed in ICVS, studying the effect of Neutrophils on Microglia after a Spinal Cord Injury, a field in which she continues to work. She is being supervised by Nuno Silva and Susana Monteiro, in a master project entitled “Sex differences in the sympathetic regulation of the immune response and functional recovery after Spinal Cord Injury”. The main goal of this dissertation is to fill an important research gap in the SCI field, by understanding how sexual dimorphism in sympathetic signaling affects SCI’s immune response, inflammation, and pathophysiology. The knowledge gathered is expected to be preponderant for future research dedicated to designing personalized therapies that take into account the specificities of each sex, improving the validity and translational potential of preclinical findings.

Scientific Highlights

Pinho, Andreia G., Andreia Monteiro, Sara Fernandes, Nídia de Sousa, António J. Salgado, Nuno A. Silva, and Susana Monteiro. 2023. “The Central Nervous System Source Modulates Microglia Function and Morphology In Vitro” International Journal of Molecular Sciences 24, no. 9: 7685. https://doi.org/10.3390/ijms24097685

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Projects

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Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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