New discovery in the treatment of Machado-Joseph disease
Researchers from ICVS identify cytalopram as a promising drug in the treatment of Machado-Joseph disease. The study was published in the renowned Brain journal.
Machado-Joseph disease (MJD) is an inherited and currently incurable neurodegenerative disease caused by a mutation in the ATXN3 gene. When modified, this gene produces an abnormal protein (ataxin-3) that forms aggregates in neurons leading to their malfunction. This results in problems in movement coordination, balance, in speech and ...
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