Alessander Leyendecker Junior

  • Mesenchymal stem cells
  • secretome
  • Parkinson’s Disease
  • neurodegenerative diseases
  • oxidative stress
  • regeneration

I have a degree in Biomedical Sciences from Universidade Federal Fluminense (Brazil) with Honours (First Class) from Monash University (Australia). I worked from August 2013 to February 2015 as a CAPES scholarship holder by the Science without Borders program, where I studied Bachelor of Biomedical Sciences at Monash University. I am a specialist in Flow Cytometry from the Faculty of Medicine of the University of São Paulo (Brazil) and a Master in Science from the Instituto Sírio-Libanês de Ensino e Pesquisa (Brazil). I am currently undertaking PhD level studies in Health Sciences at the Life and Health Sciences Research Institute (ICVS) at the University of Minho. I have strong experience in culture of mesenchymal, embryonic and induced pluripotent stem cells (IPSCs). I have experience with molecular biology techniques (example: RT-qPCR), immunophenotyping by flow cytometry, protein analysis methods (western blot, electrophoresis and ELISA), preparation of samples for histological and immunohistochemical analysis and preparation and handling of solutions. The main goal of my investigation is to develop a novel strategy for the treatment of DJ-1 (PARK7) induced Parkinson’s Disease, through the administration of the secretome of induced mesenchymal stem cells cultured in stirred suspension bioreactors under oxidative stress conditions.

Alessander Leyendecker Junior

  • Mesenchymal stem cells
  • secretome
  • Parkinson’s Disease
  • neurodegenerative diseases
  • oxidative stress
  • regeneration

I have a degree in Biomedical Sciences from Universidade Federal Fluminense (Brazil) with Honours (First Class) from Monash University (Australia). I worked from August 2013 to February 2015 as a CAPES scholarship holder by the Science without Borders program, where I studied Bachelor of Biomedical Sciences at Monash University. I am a specialist in Flow Cytometry from the Faculty of Medicine of the University of São Paulo (Brazil) and a Master in Science from the Instituto Sírio-Libanês de Ensino e Pesquisa (Brazil). I am currently undertaking PhD level studies in Health Sciences at the Life and Health Sciences Research Institute (ICVS) at the University of Minho. I have strong experience in culture of mesenchymal, embryonic and induced pluripotent stem cells (IPSCs). I have experience with molecular biology techniques (example: RT-qPCR), immunophenotyping by flow cytometry, protein analysis methods (western blot, electrophoresis and ELISA), preparation of samples for histological and immunohistochemical analysis and preparation and handling of solutions. The main goal of my investigation is to develop a novel strategy for the treatment of DJ-1 (PARK7) induced Parkinson’s Disease, through the administration of the secretome of induced mesenchymal stem cells cultured in stirred suspension bioreactors under oxidative stress conditions.

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Projects

As Leader

Projects

As Member

Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

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Enabling Technologies in CNS Repair

Recent advances in the field of electronics, miniaturisation and microfabrication and a deeper understanding of the interface between physics and living matter for sensing and neural stimulation allow us to develop new…

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