Beatriz Barros dos Santos

  • Chronic stress
  • Tau
  • RNA-binding proteins
  • Stress Granules

I am a Research fellow at ICVS in Dr. Joana Silva’s team. I am also a master’s student enrolled in the Bioinformatics master program of the School of Engineering at the University of Minho, to further develop my computational and data analysis competencies relevant to my ongoing research and future doctoral studies. Currently, I am continuing to develop the project that I started during my master’s project entitled “The unique biology of RNA-granules in Stress and Alzheimer’s Disease pathologies”, under the supervision of Joana Silva and Ioannis Sotiropoulos. In this project, we aim to further understand the mechanisms associated with stress-induced pathology and SG induction that are dysregulated by high levels of glucocorticoids and chronic stress. We also aim to understand how autophagy modulates the neurodegenerative marks, the relevance of mTOR and autophagy in the regulation of RNA homeostasis, and the translational stress response. I hold a bachelor’s in Biochemistry, and my interest in the molecular mechanisms of disease started to grow while starting my master’s in Molecular Genetics, where we study multiple molecular mechanisms in many different system organisms and disease contexts.

Beatriz Barros dos Santos

  • Chronic stress
  • Tau
  • RNA-binding proteins
  • Stress Granules

I am a Research fellow at ICVS in Dr. Joana Silva’s team. I am also a master’s student enrolled in the Bioinformatics master program of the School of Engineering at the University of Minho, to further develop my computational and data analysis competencies relevant to my ongoing research and future doctoral studies. Currently, I am continuing to develop the project that I started during my master’s project entitled “The unique biology of RNA-granules in Stress and Alzheimer’s Disease pathologies”, under the supervision of Joana Silva and Ioannis Sotiropoulos. In this project, we aim to further understand the mechanisms associated with stress-induced pathology and SG induction that are dysregulated by high levels of glucocorticoids and chronic stress. We also aim to understand how autophagy modulates the neurodegenerative marks, the relevance of mTOR and autophagy in the regulation of RNA homeostasis, and the translational stress response. I hold a bachelor’s in Biochemistry, and my interest in the molecular mechanisms of disease started to grow while starting my master’s in Molecular Genetics, where we study multiple molecular mechanisms in many different system organisms and disease contexts.

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