Beatriz Martínez-Rojas

  • CNS repair
  • Spinal cord injury
  • stem cells
  • Neural plasticity

Beatriz graduated in Biochemistry from the University of Córdoba, Spain (2013-2017), and completed a Master’s in Molecular, Cellular, and Genetic Biology at the University of Valencia, Spain (2018). She conducted her PhD thesis (2019-2023) at the Neuronal and Tissue Regeneration Lab, headed by Dr. Victoria Moreno Manzano at the CIPF (Valencia, Spain), focusing on spinal cord injury research. During her PhD, Beatriz implemented a novel approach for optogenetic stimulation of cAMP signaling in corticospinal neurons to improve motor function after spinal cord injury. She has also conducted two international research stays at the University of Copenhagen and at Imperial College London. Currently, her research focuses on engineering the MSC secretome for CNS-targeting.

Beatriz Martínez-Rojas

  • CNS repair
  • Spinal cord injury
  • stem cells
  • Neural plasticity

Beatriz graduated in Biochemistry from the University of Córdoba, Spain (2013-2017), and completed a Master’s in Molecular, Cellular, and Genetic Biology at the University of Valencia, Spain (2018). She conducted her PhD thesis (2019-2023) at the Neuronal and Tissue Regeneration Lab, headed by Dr. Victoria Moreno Manzano at the CIPF (Valencia, Spain), focusing on spinal cord injury research. During her PhD, Beatriz implemented a novel approach for optogenetic stimulation of cAMP signaling in corticospinal neurons to improve motor function after spinal cord injury. She has also conducted two international research stays at the University of Copenhagen and at Imperial College London. Currently, her research focuses on engineering the MSC secretome for CNS-targeting.

Scientific Highlights

Beatriz Martinez Rojas; Esther Giraldo; Ruben Grillo Risco; Marta R Hidalgo; Eric López Mocholí; Ana Alastrue Agudo; Francisco García García; Victoria Moreno Manzano. NPC transplantation rescues sci-driven cAMP/EPAC2 alterations, leading to neuroprotection and microglial modulation. DOI: 10.1007/s00018-022-04494-w. Cellular and Molecular Life Sciences (IF:9.2), 29/07/2022. Type of production: Scientific paper Format: Journal

Javier Monreal-Trigo; Jose Manuel Terres-Haro; Beatriz Martinez-Rojas; Maria Del Mar Sanchez-Martin; Esther Giraldo; Victoria Moreno Manzano; Miguel Alcaniz Fillol. Optogenetic Stimulation Array for Confocal Microscopy Fast Transient Monitoring. DOI: 10.1109/TBCAS.2022.3226558. IEEE Trans Biomed Circuits Syst (IF:4.75),06/12/2022.Type of production: Scientific paper Format: Journal.

Irene Cuenca-Ortolá; Beatriz Martínez Rojas; Victoria Moreno Manzano; Marcos García Castelló; Manuel Monleón Pradas; Cristina Martínez Ramos; Jorge Más Estellés. A Strategy for Magnetic and Electric Stimulation to Enhance Proliferation and Differentiation of NPCs Seeded over PLA Electrospun Membranes. DOI: 10.3390/biomedicines10112736. Biomedicines (IF: 4.7), 28/10/2022. Type of production: Scientific paper Format: Journal

Esther Giraldo; David Palmero-Canton; Beatriz Martinez-Rojas; Maria del Mar Sanchez-Martin; Victoria Moreno-Manzano. Optogenetic Modulation of Neural Progenitor Cells Improves Neuroregenerative Potential. DOI: 10.3390/ijms22010365. International Journal of Molecular Sciences (IF: 5.6), 31/12/2020.Type of production: Scientific paper Format: Journal

Sonia Hingorani, Guillem Paniagua Soriano; Carlos Sánchez Huertas; Eva María Villalba Riquelme; Eric Lopez Mocholí; Beatriz Martinez Rojas; Ana Alastrue Agudo; Sebastián Dupraz; Antonio Vicente Ferrer Montiel; Victoria Moreno Manzano. Transplantation of dorsal root ganglia overexpressing the NaChBac sodium channel improves locomotion after complete SCI. DOI: 10.1016/j.ymthe.2024.03.038. Molecular Therapy (IF:12.4), 30/03/2024. Type of production: Scientific paper Format: Journal

E. Giraldo; V.J. Nebot; S. Đorđević; R. Requejo-Aguilar; A. Alastrue-Agudo; O. Zagorodko; A.Armiñán; Beatriz Martinez-Rojas; M.J. Vicent; V.Moreno-Manzano. A rationally designed self-immolative linker enhances the synergism between a polymer-rock inhibitor conjugate and neural progenitor cells in the treatment of spinal cord injury. DOI: 10.1016/j.biomaterials.2021.121052. Biomaterials (I.F: 12.47), 29/07/2021.Type of production: Scientific paper Format: Journal

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Enabling Technologies in CNS Repair

Recent advances in the field of electronics, miniaturisation and microfabrication and a deeper understanding of the interface between physics and living matter for sensing and neural stimulation allow us to develop new…

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