Inês Caldeira

Inês Caldeira obtained her BSc degree in Biochemistry in 2019 by the Faculty of Sciences of the University of Porto. In 2022, Inês was conferred an MSc degree in Applied Biochemistry in the field of Biomedicine by the University of Minho. During this period, as an internship trainee at ICVS, her research focus included the study of new signalling pathways and molecular mechanisms involved in normal/abnormal embryonic lung development, at Rute Mouras’s lab. Recently, Inês joined Agostinho Carvalho’s group as a research fellow, where she is currently interested in exploring the influence of specific host genetic background on the activation of immunity and inflammation and how that may render individuals to susceptibility to fungal infection, namely, Invasive Pulmonary Aspergillosis.


Functional genomics of fungal disease

Genetic analysis of molecular and functional traits in immune cells, such as gene and protein expression and effector functions, offers a promising strategy for investigating phenotypic variation and dissecting the molecular mechanisms underlying propensity to infection.

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Host-fungus interaction and disease pathogenesis

The reprogramming of cellular metabolism is a fundamental mechanism whereby immune cells respond to infection. The sensing of microbial ligands by myeloid cells promotes dynamic changes in host cell metabolism to deliver a rapid source of energy to support…

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