Iodine and maternal and child’s health
Iodine deficiency is the most common cause of PREVENTABLE brain damage in infants, impairing the achievement of their full intellectual capabilities. Iodine is needed for the synthesis of thyroid hormones (TH)…
- Research
- Population Health Assessment
- Joana Almeida Palha
Joana Almeida Palha
- Thyroid hormones
- Thyroid
- Iodine
- Pregnancy
- Choroid plexus
- Blood-brain barrier
- Iron
- Iodine supplementation
- Endocrinology
Joana Palha is full professor of biochemistry at the School of Medicine, University of Minho (Braga, Portugal). PhD in Biomedical Sciences in 1995 (University of Porto, Portugal, research project at Columbia University, New York, USA), MSc in Public Health in 2016 (Karolinska Institute, Stockholm, Sweden), BSc in Biochemistry (University of Porto, Portugal). Published over 100 articles in peer-reviewed journals. Principal investigator of several research projects has supervised 15 PhD students (14 completed). She serves/has served in several national and international organizations (Present: Executive Committee of the Organisation for PhD Education in Biomedicine and Health Sciences in the European System, member of the National Council for Science, Technology and Innovation, Embassador and Member of the Scientific Council of the BIAL Foundation. Past: International Brain Research Organization, COST, Society for Neurosciences USA, Portuguese Society for Neurosciences, Portuguese Foundation for Science and Technology), evaluates for several journals and funding agencies, and is regularly member of scientific committees/chair of conferences/congresses. She started her career in 1992 on thyroid hormones, studying one of the first knock-out mouse models. She led pioneer studies that revealed an endocrine function of the blood brain barriers, particularly the choroid plexus, in brain homeostasis. She has been coordinating translational and clinical research, with focus on the endocrine axis. Her studies in humans have contributed to the change in the national policy on iodine supplementation to the Portuguese population, with specific guidelines for women in reproductive age and pregnant women.
Joana Almeida Palha
- Thyroid hormones
- Thyroid
- Iodine
- Pregnancy
- Choroid plexus
- Blood-brain barrier
- Iron
- Iodine supplementation
- Endocrinology
Joana Palha is full professor of biochemistry at the School of Medicine, University of Minho (Braga, Portugal). PhD in Biomedical Sciences in 1995 (University of Porto, Portugal, research project at Columbia University, New York, USA), MSc in Public Health in 2016 (Karolinska Institute, Stockholm, Sweden), BSc in Biochemistry (University of Porto, Portugal). Published over 100 articles in peer-reviewed journals. Principal investigator of several research projects has supervised 15 PhD students (14 completed). She serves/has served in several national and international organizations (Present: Executive Committee of the Organisation for PhD Education in Biomedicine and Health Sciences in the European System, member of the National Council for Science, Technology and Innovation, Embassador and Member of the Scientific Council of the BIAL Foundation. Past: International Brain Research Organization, COST, Society for Neurosciences USA, Portuguese Society for Neurosciences, Portuguese Foundation for Science and Technology), evaluates for several journals and funding agencies, and is regularly member of scientific committees/chair of conferences/congresses. She started her career in 1992 on thyroid hormones, studying one of the first knock-out mouse models. She led pioneer studies that revealed an endocrine function of the blood brain barriers, particularly the choroid plexus, in brain homeostasis. She has been coordinating translational and clinical research, with focus on the endocrine axis. Her studies in humans have contributed to the change in the national policy on iodine supplementation to the Portuguese population, with specific guidelines for women in reproductive age and pregnant women.
Scientific Highlights
1-Machado SI, Pereira ML, Roque S, Costeira MJ, Bordalo AA, Miranda A, Costa P, Borges N, Palha JA. Iodine Availability through Iodized Salt in Portugal: 2010-2021 Sales Evolution and Distribution. Nutrients. 2023 Mar 8;15(6):1324. doi: 10.3390/nu15061324. PMID: 36986054; PMCID: PMC10056069.
2-Roque S, de Sá-Calçada D, Cerqueira-Rodrigues B, Monteiro S, Guerreiro SG, Palha JA, Correia-Neves M. Chronic Mycobacterium avium infection differentially affects the cytokine expression profile of three mouse strains, but has no effect on behavior. Sci Rep. 2023 Apr 17;13(1):6199. doi: 10.1038/s41598-023-33121-2. PMID: 37069180; PMCID: PMC10110542.
3-Lopes-Pereira M, Quialheiro A, Costa P, Roque S, Correia Santos N, Correia-Neves M, Goios A, Carvalho I, Korevaar TIM, Vilarinho L, Palha JA. Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes. Eur Thyroid J. 2022 Jan 1;11(1):e210035. doi: 10.1530/ETJ-21-0035. PMID: 34981750.
4-Tahira A, Marques F, Lisboa B, Feltrin A, Barbosa A, de Oliveira KC, de Bragança Pereira CA, Leite R, Grinberg L, Suemoto C, de Lucena Ferretti-Rebustini RE, Pasqualucci CA, Jacob-Filho W, Brentani H, Palha JA. Are the 50’s, the transition decade, in choroid plexus aging? Geroscience. 2021 Feb;43(1):225-237. doi: 10.1007/s11357-021-00329-x. Epub 2021 Feb 12. PMID: 33576945; PMCID: PMC8050122.
5-Lopes-Pereira M, Roque S, Costa P, Quialheiro A, Santos NC, Goios A, Vilarinho L, Correia-Neves M, Palha JA. Impact of iodine supplementation during preconception, pregnancy and lactation on maternal thyroid homeostasis and offspring psychomotor development: protocol of the IodineMinho prospective study. BMC Pregnancy Childbirth. 2020 Nov 13;20(1):693. doi: 10.1186/s12884-020-03376-y. PMID: 33187482; PMCID: PMC7664061.
6-Marques F, Sousa JC, Brito MA, Pahnke J, Santos C, Correia-Neves M, Palha JA. The choroid plexus in health and in disease: dialogues into and out of the brain. Neurobiol Dis. 2017 Nov;107:32-40. doi: 10.1016/j.nbd.2016.08.011. Epub 2016 Aug 18. PMID: 27546055.
7-Costeira MJ, Oliveira P, Santos NC, Ares S, Saenz-Rico B, de Escobar GM, Palha JA. Psychomotor development of children from an iodine-deficient region. J Pediatr. 2011 Sep;159(3):447-53. doi: 10.1016/j.jpeds.2011.02.034. Epub 2011 Apr 14. PMID: 21492867.
8-Costeira MJ, Oliveira P, Ares S, Roque S, de Escobar GM, Palha JA. Parameters of thyroid function throughout and after pregnancy in an iodine-deficient population. Thyroid. 2010 Sep;20(9):995-1001. doi: 10.1089/thy.2009.0356. PMID: 20629555.
9-Costeira MJ, Oliveira P, Ares S, de Escobar GM, Palha JA. Iodine status of pregnant women and their progeny in the Minho Region of Portugal. Thyroid. 2009 Feb;19(2):157-63. doi: 10.1089/thy.2008.0249. PMID: 18976166.
10-Marques F, Falcao AM, Sousa JC, Coppola G, Geschwind D, Sousa N, Correia-Neves M, Palha JA. Altered iron metabolism is part of the choroid plexus response to peripheral inflammation. Endocrinology. 2009 Jun;150(6):2822-8. doi: 10.1210/en.2008-1610. Epub 2009 Feb 12. PMID: 19213835.”
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Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″
Copyright ©2022 ICVS. All Rights Reserved
Copyright ©2022 ICVS. All Rights Reserved
Address
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″
Copyright ©2022 ICVS. All Rights Reserved
Address
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″