João Cerqueira

  • Neuroimmunology
  • Multiple sclerosis
  • Cognition
  • Clinical trials

João José Cerqueira (JJC) is associate professor of neurology (with habilitation) and course director at the School of Medicine and principal investigator at ICVS/3B’s research institute, University of Minho, in Braga, Portugal. He is also head of the neuroimmunology clinic at Hospital de Braga and medical executive director of the 2CA – Braga, a Clinical Academic Centre fully devoted to clinical research and the number one site for clinical trials in Portugal. João’s research focuses on determinants and treatment of poor cognitive function, particularly in neuroimmune disorders. He is the author of more than 90 peer reviewed papers, with more than 2500 citations (h index 26). His work has been funded by Portuguese Science Foundation, European Union, BIAL Foundation and BIOGEN. He co-supervised 5 PhD and 6 Master students.



Cognitive deficits are common in MS. Early detection of cognitive deficits its key to achieve good outcomes and prevent further cognitive deterioration. Processing speed test is a self-applied screening test for…

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The goal of this project is to assess the impact of COVID19 vaccines in patients with multiple sclerosis treated with different…

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Devolpment of frailty index for MS

Frailty is a marker of poor clinical outcomes in healthy ageing but also in several chronic conditions. The objetive of this project is to develop a MS specific frailty…

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Recently, we used a MS animal model to perform high-throughput sequencing of astrocytes’ transcriptome during disease progression. Our data shows a surprising up-regulation of glycolytic and tricarboxylic acid (TCA) cycle…

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Cognitive deficits are common in MS but therapeutic options are lacking. Modafinil has been show to impact cognitive performance in some trials for MS-related fatigue, but it has a variable…

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The immune system in Multiple Sclerosis

This project aims to explore the immune system on multiple sclerosis pathophysiology and is divided in 3 branches:
– Tcells@MS. Our recent studies on newly diagnoses RRMS and PPMS patients…

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