Nuno A. Silva

  • Neurotrauma
  • Spinal Cord Injury
  • Molecular Therapy
  • Cell Therapy
  • Preclinical Trials

Nuno Silva received is PhD in Tissue Engineering, Regenerative Medicine and Stem Cells from the University of Minho in 2012. His PhD work consisted on the development of novel approaches for Spinal Cord Injury (SCI) Repair based on biodegradable materials and stem cells. His PhD was carried out in 3B’s Research Group and in the Centre for Cellular and Biomolecular Research of the University of Toronto. In 2012 he started a post-doc at ICVS dedicated to study the best therapeutic combination to treat the spinal cord. In 2014 he was able to capture national competitive funding and started his own lab. In 2019 his position was reinforced through a FCT CEEC grant (Assistant Researcher). The concept of his lab is based on an intimate cross talk between Pharmacotherapies, Cells Therapy, SCI animal models and basic neuroscience. He is currently an author of 50 scientific publications and has more than 2200 citations and an h-index of 22. Parallel to his research activity his has been acting as referee for several international journals, for the European Science Foundation and is part of the editorial board of 4 international journals. He was part of the scientific and organizing committees of the Spinal Cord Iberian Symposium (SCiS 2015) and was the meeting chair of the first International Meeting of the Portuguese Network on Spinal Cord Injury (MiSCI-2019). Finally, during his research career, Nuno Silva was able to capture more than 1.000.000€ of competitive funding, either as salary grants (438k) or in research projects (644k).

Scientific Highlights

“2022: Patent, INPI 117579, Dispositivo de estimulação elétrica direta para cultura de células, método e aplicações do mesmo.
2021: Prize Melo e Castro for Spinal Cord Injury Research (Co-PI).
2021: Lima et al., 2021, npj Regenerative Medicine 6: 11.
2020: Invited Lecture on the IX In4Med, NEM/AAC, Coimbra, Portugal.
2019: Chair of the Symposium on Preclinical Animal Models in Tissue Engineering & Regenerative Medicine, TERMIS-AP 2019, Brisbane, Australia.
2019: Meeting Chair of the 1st International Meeting of the Portuguese Network for Spinal Cord Injury Research, Braga, Portugal.
2018: Assistant Research Position under the Stimulus to Scientific Employment Program: CEECIND/04794/2017.
2017: Prize Melo e Castro for Spinal Cord Injury Research (Co-PI).
2017: Principal Investigator of the NORTE 2020 project NORTE-01-0145-FEDER-029968.”


Basic mechanisms of degeneration/regeneration

This project dedicates to fundamental research to understand the molecular mechanisms underlying Parkinson’s Disease (PD) and Spinal Cord Injury (SCI) pathophysiology.

In the context of PD, we focus on addressing how…

Read More

Enabling Technologies in CNS Repair

Recent advances in the field of electronics, miniaturisation and microfabrication and a deeper understanding of the interface between physics and living matter for sensing and neural stimulation allow us to develop new…

Read More

Molecular Therapies

The remarkable advances in molecular biology in the past decades have led to a better understanding of the mechanisms implicated in the pathophysiology of many CNS disorders as well as mechanisms that control axonal regeneration…

Read More