Raquel Fernandes

  • Aspergillosis
  • Itaconate
  • Immunometabolism
  • Antifungal immunity

Consuelo Micheli obtained a degree in Biological Science in 2015 and a Master degree in Molecular and Cellular Biology in 2019 awarded by the University of Pisa (Pisa, Italy). During her Master studies, she investigated the role of DNA damage and oxidative stress in lymphocytes from Systemic Lupus Erythematosus and Undifferentiated Connective Tissue Diseases patients. In 2020, Consuelo Micheli moved to Portugal, in the context of an Erasmus + project, where she joined Egídio Torrado’s research group at the Life and Health Sciences Research Institute (ICVS) to study the Mycobacterium tuberculosis infection. Currently, Consuelo Micheli is enrolled in the Ph.D. in Health Sciences from the School of Medicine (University of Minho, Braga, Portugal) where she is unravelling the immunometabolic pathways that modulate the protective immune response to Mycobacterium tuberculosis infection.

Projects

Functional genomics of fungal disease

Genetic analysis of molecular and functional traits in immune cells, such as gene and protein expression and effector functions, offers a promising strategy for investigating phenotypic variation and dissecting the molecular mechanisms underlying propensity to infection.

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Host-fungus interaction and disease pathogenesis

The reprogramming of cellular metabolism is a fundamental mechanism whereby immune cells respond to infection. The sensing of microbial ligands by myeloid cells promotes dynamic changes in host cell metabolism to deliver a rapid source of energy to support…

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