Scientific Highlights

Scientific Highlights

Articles:
– Datorre J, dos Reis MB, de Carvalho AC, Porto J, Rodrigues GH, Lima AB, dos Reis M, Hirai W, Hashimoto CL, Guimarães DP, Reis RM. Enhancing Colorectal Cancer Screening with Droplet Digital PCR (ddPCR) Analysis of Fusobacterium nucleatum in Fecal Immunochemical Test (FIT) Samples. Cancer Prevention Research, 2024 Jul 2. Online ahead of print.
– Cavagna RO, de Paula F, Berardinelli GN, Bonatelli M, Santana I, da Silva EC, Teixeira G, Zaniolo B, Dias JM, da Silva F, Silva CA, Guimarães M, Barone CP, Jacinto AA, Oliveira R, Miziara JE, de Marchi P, Molina-Vila MA, Leal LF, Reis RM. Molecular Profile of Driver Genes in Lung Adenocarcinomas of Brazilian Patients Who Have Never Smoked: Implications for Targeted Therapies. The Oncologist, 2024 Jun 29. Online ahead of print
– Senkin S, Moody S, Díaz-Gay M, Abedi-Ardekani B, Cattiaux T, Ferreiro-Iglesias A, Wang J, Fitzgerald S, Reis RM, Faria EF, de Menezes NS, Ferrari RS, Banks RE, Vasudev NS, Zaridze D, Mukeriya A, Purdue MP, Rothman N, Chanock SJ, Ueland PM, Johansson M, McKay J, Scelo G, Chanudet E, Humphreys L, de Carvalho AC, Perdomo S, Alexandrov LB, Stratton MR, Brennan P. Geographic variation of mutagenic exposures in kidney cancer genomes. Nature. 2024 May;629(8013):910-918.
– Purdue MP, Dutta D, Machiela MJ, Gorman BR, Winter T, Okuhara D, Cleland S, Ferreiro-Iglesias A, Scheet P, Liu A, Wu C, Antwi SO, Larkin J, Zequi SC, Sun M, Hikino K, Hajiran A, Neffa F, Brown KM, Hofmann JN, Rhee J, Yeager M, Cole NR, Hicks BD, Manning MR, Hutchinson AA, Rothman N, Huang WY, Linehan WM, Lori A, Ferragu M, Zidane-Marinnes M, Serrano SV, Magnabosco WJ; BioBank Japan Project; Vilas A, Decia R, Carusso F, Graham LS, Anderson K, Reis RM, Colli L, Finelli A, Houlston R, Eckel-Passow J, Abbosh P, Ganna A, Brennan P, Gu J, Chanock SJ. Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions. Nature Genetics, 2024 May;56(5):809-818.
– Vázquez-Iglesias L, Casagrande G, García-Lojo D, Leal LF, Ngo T, Pérez-Juste J, Reis RM, Kant K, Pastoriza-Santos I. SERS sensing for cancer biomarker: Approaches and directions. Bioactive Materials. Volume 34, April 2024, 248-268.
– Campanella NC, Gomes I, Alves AL, Leal LF, Evangelista AF, Rosa MN, Melendez ME, Silva VAO, Dias R, Abrahão-Machado L, 6 Santana I, Martinho O, Guimarães DP, Faça VM, Reis RM. Biological and therapeutic implications of RKIP in gastrointestinal stromal tumor (GIST): an integrated transcriptomic and proteomic analysis. Cancer Cell International, 2023 Oct 31;23(1):256. doi: 10.1186/s12935-023-03102-6.
– Fares A, Li Yao, Jiang M, Brown C, Lam A, Aggarwal R, Leal LF, Davies M, Mates A, Savic M, Brenner H, Cox A, Field JK, Ruano-Ravina A, Shete S, Tardon A, Wang Y, Le Marchand L, Reis RM, Schabath MB, Goodman G, Chen C, Shen H, Ryan M, Landi MT, Shiraishi T, Zhang J, Schwartz G, Tsao M, Christiani DC, Yang P, Hung R, Xu W, Liu G. Duration of smoking abstinence before non-small cell lung cancer (NSCLC) diagnosis, overall and NSCLC-specific survival: A pooled, retrospective cohort study. The Lancet Public Health, 2023 Sep;8(9):e691-e700. doi: 10.1016/S2468-2667(23)00131-7.
– Marques RP, Moreno DA, Da Silva L, Leal LF, de Paula FE, Santana I, Teixeira G, Saggioro F, Neder L, Junior CA, Mançano B, Reis RM. Digital expression profile of immune checkpoints genes in medulloblastomas identifies CD24 and CD276 as putative immunotherapy targets. Frontiers in Immunology, 2023, 14:1062856.
– Pinto F, Costa ÂM, Matsushita MM, Costa S, Silva VA, Lopes CM, Clara CA, Becker AP, Neder L, Hajj GN, da Cunha IW, Jones C, Andrade RP, Reis RM. The T-box transcription factor brachyury behaves as a tumor suppressor in gliomas. Journal of Pathology. 2020 May;251(1):87-99.

Book Chapter:
Ohgaki H, Biernat W, Reis RM, Hegi M, Kleihues P. Gliosarcoma. In: WHO Classification of Tumours. Pathology and Genetics of Tumours of the Nervous System. Kleihues P. and Cavenee WK (eds), IARC Press: Lyon, 2000.

Prize:
– 50-for-50: Empowering future cancer research leaders. International Agency for Research on Cancer, Lyon, France 6-10 June, 2016.
– Pfizer/Sociedade de Ciências Médicas de Lisboa Prize in “Research in Oncology Diseases, Prof. Francisco Gentil, 2006, Portugal