Sofia Silva

  • Neurodegeneration
  • Proteostasis
  • Aging
  • C. elegans
  • Pharmacological Therapies

Sofia Silva holds a B.Sc. in Biochemistry from the School of Sciences, University of Minho (2025), and is currently pursuing a Master’s degree in Biomedicine at the University of Minho’s School of Medicine. She is carrying out her dissertation project at the Life and Health Sciences Research Institute (ICVS), under the supervision of Andreia Teixeira-Castro and Marta D. Costa.

Her research focuses on identifying and characterizing novel compounds that enhance proteostasis, with potential applications in anti-aging and anti-neurodegenerative therapies. Using Caenorhabditis elegans models, her work combines phenotypic screening, biochemical approaches, and drug discovery strategies to improve protein homeostasis and reduce disease-associated phenotypes.

Sofia Silva

  • Neurodegeneration
  • Proteostasis
  • Aging
  • C. elegans
  • Pharmacological Therapies

Sofia Silva holds a B.Sc. in Biochemistry from the School of Sciences, University of Minho (2025), and is currently pursuing a Master’s degree in Biomedicine at the University of Minho’s School of Medicine. She is carrying out her dissertation project at the Life and Health Sciences Research Institute (ICVS), under the supervision of Andreia Teixeira-Castro and Marta D. Costa.

Her research focuses on identifying and characterizing novel compounds that enhance proteostasis, with potential applications in anti-aging and anti-neurodegenerative therapies. Using Caenorhabditis elegans models, her work combines phenotypic screening, biochemical approaches, and drug discovery strategies to improve protein homeostasis and reduce disease-associated phenotypes.

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Projects

As Leader

Projects

As Member

Serotonin signaling and proteostasis

This project addresses an unmet medical need- the lack of effective treatment for any of the aging-associated neurodegenerative diseases. Due to the worldwide aging of the population, by 2050 it is expected that over 135 million people…

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