Susana Roque

Neuroimmunology
Cytokines
Mood disorders, Cognitive function
Iodine
Neurodevelopment

My main field of study is neuroimmunology, namely the role of the immune system in neuropsychiatric disorders and cognitive function. To further understand the etiology of psychiatric and immune system disorders and cognitive function, I am also collaborating with research projects that assess the factors that could impact on fetal and infant development (such as iodine supplementation, microbiome alterations) using human samples and animal models. I am a Junior Researcher at the Life and Health Sciences Research Institute, University of Minho. I have been part of 12 research projects that resulted on 37 publications (9 of them as a first author) with 131 co-authors, a cumulative impact factor of 196, a total of 1032 citations and a H-index of 16 (Web of Science).

Susana Roque

Neuroimmunology
Cytokines
Mood disorders, Cognitive function
Iodine
Neurodevelopment

Scientific Highlights

Roque S, de Sa-Calcada D, Cerqueira-Rodrigues B, et al. Chronic Mycobacterium avium infection differentially affects the cytokine expression profile of three mouse strains, but has no effect on behavior. Sci Rep. Apr 17 2023;13(1):6199. doi:10.1038/s41598-023-33121-2
Machado SI, Pereira ML, Roque S, et al. Iodine Availability through Iodized Salt in Portugal: 2010-2021 Sales Evolution and Distribution. Nutrients. Mar 8 2023;15(6)doi:10.3390/nu15061324
Serre-Miranda C, Roque S, Barreira-Silva P, et al. Age-Related Sexual Dimorphism on the Longitudinal Progression of Blood Immune Cells in BALB/cByJ Mice. J Gerontol A Biol Sci Med Sci. May 5 2022;77(5):883-891. doi:10.1093/gerona/glab330
Lopes-Pereira M, Quialheiro A, Costa P, et al. Iodine supplementation: compliance and association with adverse obstetric and neonatal outcomes. Eur Thyroid J. Jan 1 2022;11(1)doi:10.1530/ETJ-21-0035
Gallo V, Team I, Gentile R, Antonini G, Iacobelli S. Increased Gal-3BP plasma levels in hospitalized patients infected with SARS-CoV-2. Clin Exp Med. Jan 25 2022;doi:10.1007/s10238-021-00788-8
Bonifacio Andrade E, Lorga I, Roque S, et al. Maternal vaccination against group B Streptococcus glyceraldehyde-3-phosphate dehydrogenase leads to gut dysbiosis in the offspring. Brain Behav Immun. Jul 2022;103:186-201. doi:10.1016/j.bbi.2022.04.004
Serre-Miranda C, Nobrega C, Roque S, et al. Performance assessment of 11 commercial serological tests for SARS-CoV-2 on hospitalised COVID-19 patients. Int J Infect Dis. Mar 2021;104:661-669. doi:10.1016/j.ijid.2021.01.038
Lopes-Pereira M, Roque S, Costa P, et al. Impact of iodine supplementation during preconception, pregnancy and lactation on maternal thyroid homeostasis and offspring psychomotor development: protocol of the IodineMinho prospective study. BMC Pregnancy Childbirth. Nov 13 2020;20(1):693. doi:10.1186/s12884-020-03376-y
Roque S, Mesquita AR, Palha JA, Sousa N, Correia-Neves M. The behavioral and immunological impact of maternal separation: a matter of timing. Frontiers in behavioral neuroscience. 2014;8:192. doi:10.3389/fnbeh.2014.00192

10. Roque S, Oliveira TG, Nobrega C, et al. Interplay between Depressive-Like Behavior and the Immune System in an Animal Model of Prenatal Dexamethasone Administration. Frontiers in behavioral neuroscience. 2011;5:4. doi:10.3389/fnbeh.2011.00004

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Projects

As Leader

Projects

As Member

Joana Almeida Palha

Iodine and maternal and child’s health

Iodine deficiency is the most common cause of PREVENTABLE brain damage in infants, impairing the achievement of their full intellectual capabilities. Iodine is needed for the synthesis of thyroid hormones (TH)…