Probing the future of triple Artemisinin-based combination therapy um Angola
There is still no cure for HIV infection and the extensive viral genetic diversity represents the one of the biggest obstacles to develop an effective therapy…
- Research
- Pathogen Evolutionary Genomics and Experimental Genetics
- Claudia Fançony
Claudia Fançony
- Malaria
- drug resistance
- Angola
Cláudia Fançony is graduated in Applied Biology from the University of Minho and has a PhD in Public Health from the Institute of Public Health of the University of Porto (Portugal). Cláudia is a researcher working at the Health Research Center of Angola and at the ICVS, whose main interests are antimalarial drug resistance and malaria molecular epidemiology. She is now leading a project exploring the opposing forces that two drugs exert on a single target of the malaria parasite, which are likely to potentiate incompatible resistance mechanisms. Although there are many new drugs to be developed, they may not be available in the short term. An innovative alternative would be to rescue drugs already in use in Angola and create a new combination, in turn based on pharmacogenetic evidence.
Claudia Fançony
- Malaria
- drug resistance
- Angola
Cláudia Fançony is graduated in Applied Biology from the University of Minho and has a PhD in Public Health from the Institute of Public Health of the University of Porto (Portugal). Cláudia is a researcher working at the Health Research Center of Angola and at the ICVS, whose main interests are antimalarial drug resistance and malaria molecular epidemiology. She is now leading a project exploring the opposing forces that two drugs exert on a single target of the malaria parasite, which are likely to potentiate incompatible resistance mechanisms. Although there are many new drugs to be developed, they may not be available in the short term. An innovative alternative would be to rescue drugs already in use in Angola and create a new combination, in turn based on pharmacogenetic evidence.
Scientific Highlights
https://gulbenkian.pt/videos/claudia-fancony/
Zinc Deficiency Interacts with Intestinal/Urogenital Parasites in the Pathway to Anemia in Preschool Children, Bengo-Angola.
Fançony C, Soares Â, Lavinha J, Brito M.Nutrients. 2022 Mar 27;14(7):1392. doi: 10.3390/nu14071392.
Plasmodium falciparum Multidrug Resistance Proteins (pfMRPs).
Gil JP, Fançony C.Front Pharmacol. 2021 Nov 1;12:759422. doi: 10.3389/fphar.2021.759422.
Effectiveness of Nutrition and WASH/malaria educational community-based interventions in reducing anemia in children from Angola.
Fançony C, Soares Â, Lavinha J, Barros H, Brito M.Sci Rep. 2021 Mar 10;11(1):5603. doi: 10.1038/s41598-021-85006-x.
Anemia in preschool children from Angola: a review of the evidence.
Fançony C, Lavinha J, Brito M, Barros H.Porto Biomed J. 2020 Feb 11;5(1):e60. doi: 10.1097/j.pbj.0000000000000060.
Iron deficiency anaemia among 6-to-36-month children from northern Angola.
Fançony C, Soares Â, Lavinha J, Barros H, Brito M.BMC Pediatr. 2020 Jun 17;20(1):298. doi: 10.1186/s12887-020-02185-8.
Schistosomiasis and soil-transmitted helminthiasis preventive chemotherapy: Adverse events in children from 2 to 15 years in Bengo province, Angola.
Lemos M, Pedro JM, Fançony C, Moura S, Brito M, Nery SV, Sousa CP, Barros H.PLoS One. 2020 Mar 11;15(3):e0229247. doi: 10.1371/journal.pone.0229247.
Integrated community-based intervention for urinary schistosomiasis and soil-transmitted helminthiasis in children from Caxito, Angola.
Lemos M, Fançony C, Moura S, Mirante C, Sousa P, Barros H, Nery S, Brito M.Int Health. 2020 Feb 12;12(2):86-94. doi: 10.1093/inthealth/ihz055.
Efficacy of Nutrition and WASH/Malaria Educational Community-Based Interventions in Reducing Anemia in Preschool Children from Bengo, Angola: Study Protocol of a Randomized Controlled Trial.
Fançony C, Soares Â, Lavinha J, Barros H, Brito M.Int J Environ Res Public Health. 2019 Feb 5;16(3):466. doi: 10.3390/ijerph16030466.
Plasmodium falciparum drug resistance in Angola.
Fançony C, Brito M, Gil JP.Malar J. 2016 Feb 9;15:74. doi: 10.1186/s12936-016-1122-z.
Impact of a training course on the quality of malaria diagnosis by microscopy in Angola.
Moura S, Fançony C, Mirante C, Neves M, Bernardino L, Fortes F, Sambo Mdo R, Brito M.Malar J. 2014 Nov 18;13:437. doi: 10.1186/1475-2875-13-437.
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Defining drug resistance pathways in the malaria parasite
Hampering malaria control and elimination efforts is the resilient capacity of the parasite Plasmodium falciparum to develop resistance, including resistance to the presently…
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Life and Health Sciences
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Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″
Copyright ©2022 ICVS. All Rights Reserved
Copyright ©2022 ICVS. All Rights Reserved
Address
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″
Copyright ©2022 ICVS. All Rights Reserved
Address
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″