Scientific Highlights
Articles
Vilasboas-Campos, D., Costa, M. D., Teixeira-Castro, A., Rios, R., Silva, F. G., Bessa, C., Dias, A. C. P., & Maciel, P. (2021). Neurotherapeutic effect of Hyptis spp. leaf extracts in Caenorhabditis elegans models of tauopathy and polyglutamine disease: Role of the glutathione redox cycle. Free Radical Biology & Medicine, 162, 202–215. https://doi.org/10.1016/j.freeradbiomed.2020.10.018
Vilasboas-Campos, D., Costa, M. D., Teixeira-Castro, A., Rios, R., Silva, F. G., Aierken, A., Zhang, X., Bessa, C., Dias, A. C. P., & Maciel, P. (2020). Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases. Data in brief, 33, 106598. https://doi.org/10.1016/j.dib.2020.106598
Raposo, M., Bettencourt, C., Melo, A. R. V., Ferreira, A. F., Alonso, I., Silva, P., Vasconcelos, J., Kay, T., Saraiva-Pereira, M. L., Costa, M. D., Vilasboas-Campos, D., Bettencourt, B. F., Bruges-Armas, J., Houlden, H., Heutink, P., Jardim, L. B., Sequeiros, J., Maciel, P., & Lima, M. (2022). Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing. Neurobiology of disease, 162, 105578. https://doi.org/10.1016/j.nbd.2021.105578
Jalles, A.*, Vieira, C.*, Pereira-Sousa, J., Vilasboas-Campos, D., Mota, A. F., Vasconcelos, S., Ferreira-Lomba, B., Costa, M. D., Da Silva, J. D., Maciel, P., & Teixeira-Castro, A. (2022). Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D2 and Serotonin 1A and 2A Receptors in C. elegans. Biomedicines, 10(2), 370. https://doi.org/10.3390/biomedicines10020370
Pereira-Sousa, J., Ferreira-Lomba, B., Bellver-Sanchis, A., Vilasboas-Campos, D., Fernandes, J. H., Costa, M. D., Varney, M. A., Newman-Tancredi, A., Maciel, P., & Teixeira-Castro, A. (2021). Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease. Neurobiology of disease, 152, 105278. https://doi.org/10.1016/j.nbd.2021.105278