Nuno S. Osório
Principal Investigator
Project Leader
Phylodynamic studies on SARS-CoV-2 and its application to improve viral detection and prevent transmission.
The extremely high human-to-human transmissibility of SARS-CoV-2 allows the generation of thousands of mutations within its genome fueling the evolution and selection of several viral lineages with different characteristics. While several of these lineages become rare, others largely increase in prevalence, potentially jeopardizing the efficacy of vaccines and epidemic control strategies. SARS-CoV-2 is widely spread globally and is still responsible for large mobility/mortality and economical burden. This project focus on investigating molecular factors that mediate genomic evolution of SARS-CoV-2 aiming to provide knowledge to advance current viral detection and transmission preventing strategies.
Funding Agency
FCT
Project Reference
–
Project Members
Maria Isabel Veiga
Principal Investigator
Main Project Outcomes
S. Queirós, “Right ventricular segmentation in multi-view cardiac MRI using a unified U-net model”, in E. Puyol Antón et al. (eds) Statistical Atlases and Computational Models of the Heart. Multi-Disease, Multi-View, and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge. STACOM 2021. Lecture Notes in Computer Science, vol 13131, pp. 287-295, Springer, Cham, 2022.
“Best Paper Award in the M&Ms-2 Challenge”, by M&Ms2 Challenge organizers and the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society.
Main Project Outcomes
Publications
Development of an Ultraviolet-C Irradiation Room in a Public Portuguese Hospital for Safe Re-Utilization of Personal Protective Respirators.
Padrão J, Nicolau T, Felgueiras HP, Calçada C, Veiga MI, Osório NS, Martins MS, Dourado N, Taveira-Gomes A, Ferreira F, Zille A.Int J Environ Res Public Health. 2022 Apr 16;19(8):4854. doi: 10.3390/ijerph19084854.PMID: 35457722
OmniSARS2: A Highly Sensitive and Specific RT-qPCR-Based COVID-19 Diagnostic Method Designed to Withstand SARS-CoV-2 Lineage Evolution.
Carvalho-Correia E, Calçada C, Branca F, Estévez-Gómez N, De Chiara L, Varela N, Gallego-García P, Posada D, Sousa H, Sousa J, Veiga MI, Osório NS.Biomedicines. 2021 Sep 26;9(10):1314. doi: 10.3390/biomedicines9101314.PMID: 34680431
SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal
Authors: Vítor Borges; Joana Isidro; Nídia Sequeira Trovão; … Portuguese network for SARS-CoV-2 genomics (Consortium); see more
Published:Jan 2022 in Communications Medicine
DOI: 10.1038/S43856-022-00072-0
Massive dissemination of a SARS-CoV-2 Spike Y839 variant in Portugal
Authors: Borges, Vitor; Isidro, Joana; Cortes-Martins, Helena; … Gomes, Joao Paulo; see more
Published:Jan 2020 in Emerging Microbes & Infections
DOI: 10.1080/22221751.2020.1844552
Implication of SARS-CoV-2 evolution in the sensitivity of RT-qPCR diagnostic assays.
Osório NS, Correia-Neves M.Lancet Infect Dis. 2021 Feb;21(2):166-167. doi: 10.1016/S1473-3099(20)30435-7. Epub 2020 May 28.PMID: 32473662
Contact us
Phone: +351 253 604 967
Fax: +351 253 604 809
Email: icvs.sec@med.uminho.pt
Address
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″
Copyright ©2022 ICVS. All Rights Reserved
Copyright ©2022 ICVS. All Rights Reserved
Address
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″
Copyright ©2022 ICVS. All Rights Reserved
Address
Life and Health Sciences
Research Institute (ICVS)
School of Medicine,
University of Minho,
Campus de Gualtar
4710-057 Braga
Portugal
GPS: +41° 33′ 47.33″, -8° 24′ 3.39″