Nuno S. Osório

  • Evolution
  • Bioinformatics
  • Pathogens
  • Infection
  • Tuberculosis
  • HIV
  • Biology

Nuno S. Osório is a Biologist and a PhD in Health Sciences graduated from University of Minho, Portugal, having also received advanced training in Wageningen University, The Netherlands, and University of Rochester, USA. Nuno’s research interests focus on the evolution and genetic diversity of human pathogens, including M. tuberculosis and HIV-1, relying on bioinformatics to analyze ‘omics’ data. He co-authored more than 35 scientific publications in peer-reviewed international journals including Nature Medicine, Nature Communications, Molecular Biology and Evolution, The Lancet Infectious Diseases, among others. His research advanced the state-of-the-art of relevant human infectious diseases and was disseminated in national and international media. He volunteers as Editor for several international scientific journals and is regularly invited for peer reviewing, grant evaluation and examiner in the dissertation of candidates for PhD and master’s degrees. He has 16 years of experience as university teacher in Portugal and was also invited to teach advanced courses internationally including an EMBO course on Single-Cell Genomics. In the last decade, he also coordinated, at the School of Medicine of University of Minho, several relevant activities to promote science and health literacy in the society.

Scientific Highlights

“Papers:Carvalho-Correia, E., Calçada, C., Branca, F., Estévez-Gómez, N., De Chiara, L., Varela, N., Gallego-García, P., Posada, D., Sousa, H., Sousa, J., Veiga, M. I., & Osório, N. S. (2021). OmniSARS2: A Highly Sensitive and Specific RT-qPCR-Based COVID-19 Diagnostic Method Designed to Withstand SARS-CoV-2 Lineage Evolution. In Biomedicines (Vol. 9, Issue 10, p. 1314). MDPI AG.
Rocha, D. M. G. C., Magalhães, C., Cá, B., Ramos, A., Carvalho, T., Comas, I., Guimarães, J. T., Bastos, H. N., Saraiva, M., & Osório, N. S. (2021). Heterogeneous Streptomycin Resistance Level Among Mycobacterium tuberculosis Strains From the Same Transmission Cluster. In Frontiers in Microbiology (Vol. 12). Frontiers Media SA.
Osório, N. S., & Correia-Neves, M. (2021). Implication of SARS-CoV-2 evolution in the sensitivity of RT-qPCR diagnostic assays. In The Lancet Infectious Diseases (Vol. 21, Issue 2, pp. 166–167). Elsevier BV.
Andrade, C. M., Fleckenstein, H., Thomson-Luque, R., Doumbo, S., Lima, N. F., Anderson, C., Hibbert, J., Hopp, C. S., Tran, T. M., Li, S., Niangaly, M., Cisse, H., Doumtabe, D., Skinner, J., Sturdevant, D., Ricklefs, S., Virtaneva, K., Asghar, M., Homann, M. V., … Portugal, S. (2020). Increased circulation time of Plasmodium falciparum underlies persistent asymptomatic infection in the dry season. In Nature Medicine (Vol. 26, Issue 12, pp. 1929–1940). Springer Science and Business Media LLC.
Gonçalves, S. M., Duarte-Oliveira, C., Campos, C. F., Aimanianda, V., ter Horst, R., Leite, L., Mercier, T., Pereira, P., Fernández-García, M., Antunes, D., Rodrigues, C. S., Barbosa-Matos, C., Gaifem, J., Mesquita, I., Marques, A., Osório, N. S., Torrado, E., Rodrigues, F., Costa, S., … Carvalho, A. (2020). Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity. In Nature Communications (Vol. 11, Issue 1). Springer Science and Business Media LLC.
Sousa, J., Cá, B., Maceiras, A. R., Simões-Costa, L., Fonseca, K. L., Fernandes, A. I., Ramos, A., Carvalho, T., Barros, L., Magalhães, C., Chiner-Oms, Á., Machado, H., Veiga, M. I., Singh, A., Pereira, R., Amorim, A., Vieira, J., Vieira, C. P., Bhatt, A., … Saraiva, M. (2020). Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production. In Nature Communications (Vol. 11, Issue 1). Springer Science and Business Media LLC.
Araújo, P. M. M., Carvalho, A., Pingarilho, M., Abecasis, A. B., & Osório, N. S. (2019). Characterization of a large cluster of HIV-1 A1 infections detected in Portugal and connected to several Western European countries. In Scientific Reports (Vol. 9, Issue 1). Springer Science and Business Media LLC.
Araújo, P. M. M., Martins, J. S., & Osório, N. S. (2019). SNAPPy: A snakemake pipeline for scalable HIV-1 subtyping by phylogenetic pairing. In Virus Evolution (Vol. 5, Issue 2). Oxford University Press (OUP).
Carvalho, A., Costa, P., Triunfante, V., Branca, F., Rodrigues, F., Santos, C. L., Correia-Neves, M., Saraiva, M., Lecour, H., Castro, A. G., Pedrosa, J., & Osório, N. S. (2015). Analysis of a Local HIV-1 Epidemic in Portugal Highlights Established Transmission of Non-B and Non-G Subtypes. In E. Munson (Ed.), Journal of Clinical Microbiology (Vol. 53, Issue 5, pp. 1506–1514). American Society for Microbiology.
Osório, N. S., Rodrigues, F., Gagneux, S., Pedrosa, J., Pinto-Carbó, M., Castro, A. G., Young, D., Comas, I., & Saraiva, M. (2013). Evidence for Diversifying Selection in a Set of Mycobacterium tuberculosis Genes in Response to Antibiotic- and Nonantibiotic-Related Pressure. In Molecular Biology and Evolution (Vol. 30, Issue 6, pp. 1326–1336). Oxford University Press (OUP).