The Guimarães cohort study of cardiovascular risk assessment

The Guimarães Cohort. A comprehensive evaluation of 3038 subjects concerning CV risk.

Funding Agency


Project Reference

Project Members

Main Project Outcomes

S. Queirós, “Right ventricular segmentation in multi-view cardiac MRI using a unified U-net model”, in E. Puyol Antón et al. (eds) Statistical Atlases and Computational Models of the Heart. Multi-Disease, Multi-View, and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge. STACOM 2021. Lecture Notes in Computer Science, vol 13131, pp. 287-295, Springer, Cham, 2022.

“Best Paper Award in the M&Ms-2 Challenge”, by M&Ms2 Challenge organizers and the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society.

Main Project Outcomes

Laurent S, Boutouyrie P, Cunha PG, Lacolley P, Nilsson PM. Concept of Extremes in Vascular Aging. Hypertension. 2019 Aug;74(2):218-228. doi: 10.1161/HYPERTENSIONAHA.119.12655. Epub 2019 Jun 17. PMID: 31203728.
Guimarães Cunha P, Stolarz-Skrzypek K, Persu A. Increased Blood Pressure Variability May Herald Cognitive Decline and Dementia. Hypertension. 2020 Oct;76(4):1076-1078. doi: 10.1161/HYPERTENSIONAHA.120.14785. Epub 2020 Sep 9. PMID: 32903107.
Cavero-Redondo I, Tudor-Locke C, Álvarez-Bueno C, Cunha PG, Aguiar EJ, Martínez-Vizcaíno V. Steps per Day and Arterial Stiffness. Hypertension. 2019 Feb;73(2):350-363. doi: 10.1161/HYPERTENSIONAHA.118.11987. PMID: 30624991.
Ferreira JMM, Cunha P, Carneiro A, Vila I, Cunha C, Silva C, Longatto-Filho A, Mesquita A, Cotter J, Mansilha A, Correia-Neves M. Sarcopenia as a Prognostic Factor in Peripheral Arterial Disease: Descriptive Review. Ann Vasc Surg. 2021 Jul;74:460-474. doi: 10.1016/j.avsg.2021.01.076. Epub 2021 Feb 5. PMID: 33556522.
Laurent S, Chatellier G, Azizi M, Calvet D, Choukroun G, Danchin N, Delsart P, Girerd X, Gosse P, Khettab H, London G, Mourad JJ, Pannier B, Pereira H, Stephan D, Valensi P, Cunha P, Narkiewicz K, Bruno RM, Boutouyrie P; SPARTE Investigators. SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk. Hypertension. 2021 Sep;78(4):983-995. doi: 10.1161/HYPERTENSIONAHA.121.17579. Epub 2021 Aug 30. PMID: 34455813; PMCID: PMC8415523.
Zanoli L, Briet M, Empana JP, Cunha PG, Mäki-Petäjä KM, Protogerou AD, Tedgui A, Touyz RM, Schiffrin EL, Spronck B, Bouchard P, Vlachopoulos C, Bruno RM, Boutouyrie P; Association for Research into Arterial Structure, Physiology (ARTERY) Society, the European Society of Hypertension (ESH) Working Group on Vascular Structure and Function, and the European Network for Noninvasive Investigation of Large Arteries. Vascular consequences of inflammation: a position statement from the ESH Working Group on Vascular Structure and Function and the ARTERY Society. J Hypertens. 2020 Sep;38(9):1682-1698. doi: 10.1097/HJH.0000000000002508. PMID: 32649623; PMCID: PMC7610698.
Scuteri A, Benetos A, Sierra C, Coca A, Chicherio C, Frisoni GB, Gasecki D, Hering D, Lovic D, Manios E, Petrovic M, Qiu C, Shenkin S, Tzourio C, Ungar A, Vicario A, Zaninelli A, Cunha PG. Routine assessment of cognitive function in older patients with hypertension seen by primary care physicians: why and how-a decision-making support from the working group on ‘hypertension and the brain’ of the European Society of Hypertension and from the European Geriatric Medicine Society. J Hypertens. 2021 Jan;39(1):90-100. doi: 10.1097/HJH.0000000000002621. PMID: 33273363.
Alvarez-Bueno C, Cunha PG, Martinez-Vizcaino V, Pozuelo-Carrascosa DP, Visier-Alfonso ME, Jimenez-Lopez E, Cavero-Redondo I. Arterial Stiffness and Cognition Among Adults: A Systematic Review and Meta-Analysis of Observational and Longitudinal Studies. J Am Heart Assoc. 2020 Mar 3;9(5):e014621. doi: 10.1161/JAHA.119.014621. Epub 2020 Feb 28. PMID: 32106748; PMCID: PMC7335587.
Nilsson PM, Laurent S, Cunha PG, Olsen MH, Rietzschel E, Franco OH, Ryliškytė L, Strazhesko I, Vlachopoulos C, Chen CH, Boutouyrie P, Cucca F, Lakatta EG, Scuteri A; Metabolic syndrome, Arteries REsearch (MARE) Consortium. Characteristics of healthy vascular ageing in pooled population-based cohort studies: the global Metabolic syndrome and Artery REsearch Consortium. J Hypertens. 2018 Dec;36(12):2340-2349. doi: 10.1097/HJH.0000000000001824. PMID: 30063641; PMCID: PMC6528679.
Cunha PG, Cotter J, Oliveira P, Vila I, Boutouyrie P, Laurent S, Nilsson PM, Scuteri A, Sousa N. Pulse wave velocity distribution in a cohort study: from arterial stiffness to early vascular aging. J Hypertens. 2015 Jul;33(7):1438-45. doi: 10.1097/HJH.0000000000000565. PMID: 25827429.
Herbert A, Cruickshank JK, Laurent S, Boutouyrie P; Reference Values for Arterial Measurements Collaboration. Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors. Eur Heart J. 2014 Nov 21;35(44):3122-33. doi: 10.1093/eurheartj/ehu293. Epub 2014 Aug 11. PMID: 25112663.