Influence of individual differences in reward sensitivity on the modulation of cognitive-motivational interactions in patients with obsessive-compulsive disorder

Motivational contingencies may improve or worsen our executive functioning. The effects of reward on behavior have been widely studied and may be involved in the physiopathology of obsessive-compulsive disorder (OCD). Nonetheless, it is not known (i) which are the brain systems modulating the interactions between executive and motivational processes, (ii) how these are modulated by individual differences in reward sensitivity, and (iii) which is the relevance of these processes in the context of OCD. This project aims to analyze the brain correlates of the interaction between cognitive and motivational processes in OCD, considering individual differences in personality. Specifically, we intend to shed light over the brain mechanisms underlying individual differences in the Brain Activation System (BAS)(Gray, 1987), which modulates the interaction between these processes, and to explore whether the impulse control deficits present in OCD may be better understood from this perspective.

Funding Agency

Clinical Academic Center-Braga (2CA-Braga)

Hospital de Braga

Project Reference


Project Members

Main Project Outcomes

S. Queirós, “Right ventricular segmentation in multi-view cardiac MRI using a unified U-net model”, in E. Puyol Antón et al. (eds) Statistical Atlases and Computational Models of the Heart. Multi-Disease, Multi-View, and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge. STACOM 2021. Lecture Notes in Computer Science, vol 13131, pp. 287-295, Springer, Cham, 2022.

“Best Paper Award in the M&Ms-2 Challenge”, by M&Ms2 Challenge organizers and the Medical Image Computing and Computer Assisted Intervention (MICCAI) Society.